Evidence map›Paper›PMID 38397908›Full record

ArticleBiomedicines2024

Therapeutic Potential of Cannabinoid Profiles Identified in

Pedro Wong-Salgado, Fabiano Soares, Jeel Moya-Salazar, José F Ramírez-Méndez, Marcia M Moya-Salazar, Alfonso Apesteguía, Americo Castro

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Finally Freed-Plants (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Pedro Wong-SalgadoCANNAVITAL, Clínica Especializada en Terapias con Cannabinoides, Lima 15022, Peru.
Fabiano SoaresRENATU Research Group, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima 15039, Peru.
Jeel Moya-SalazarFaculties of Health Science, Universidad Privada del Norte, Lima 15001, Peru.
José F Ramírez-MéndezCANNAVITAL, Clínica Especializada en Terapias con Cannabinoides, Lima 15022, Peru.
Marcia M Moya-SalazarCentro de Estudios del Cannabis del Perú, Lima 15022, Peru.
Alfonso ApesteguíaCentro de Información, Control Toxicológico y Apoyo a la Gestión Ambiental CICOTOX, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima 15039, Peru.
Americo CastroRENATU Research Group, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima 15039, Peru.
Centro Peruano de Estudios Sociales · PENational University of San Marcos · PEPrivate University of the North · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabis is a plant that is cultivated worldwide, and its use is internationally regulated, but some countries have been regulating its medicinal, social, and industrial uses. This plant must have arrived in Peru during the Spanish conquest and remains widely cultivated illicitly or informally to this day. However, new regulations are currently being proposed to allow its legal commercialization for medicinal purposes. Cannabis contains specific metabolites known as cannabinoids, some of which have clinically demonstrated therapeutic effects. It is now possible to quantitatively measure the presence of these cannabinoids in dried inflorescences, thus allowing for description of the chemical profile or "chemotype" of cannabinoids in each sample. This study analyzed the chemotypes of eight samples of dried inflorescences from cannabis cultivars in four different regions of Peru, and based on the significant variation in the cannabinoid profiles, we suggest their therapeutic potential. The most important medical areas in which they could be used include the following: they can help manage chronic pain, they have antiemetic, anti-inflammatory, and antipruritic properties, are beneficial in treating duodenal ulcers, can be used in bronchodilators, in muscle relaxants, and in treating refractory epilepsy, have anxiolytic properties, reduce sebum, are effective on Methicillin-resistant Staphylococcus aureus, are proapoptotic in breast cancer, can be used to treat addiction and psychosis, and are effective on MRSA, in controlling psoriasis, and in treating glioblastoma, according to the properties of their concentrations of cannabidiol, cannabigerol, and Δ9-tetrahydrocannabinol, as reviewed in the literature. On the other hand, having obtained concentrations of THC, we were able to suggest the psychotropic capacity of said samples, one of which even fits within the legal category of "non-psychoactive cannabis" according to Peruvian regulations.

Indexed as

cannabinoidschemical profileinflorescencesmedical cannabisPerutetrahydrocannabinoltherapeutic potential

Identifiers

PMID38397908
PMCPMC10886879
OpenAlexW4391324294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.