Evidence map›Paper›PMID 38397776›Full record

ReviewAntioxidants (Basel, Switzerland)2024

Management of the Brain: Essential Oils as Promising Neuroinflammation Modulator in Neurodegenerative Diseases.

Rosanna Avola, Alessandro Giuseppe Furnari, Adriana Carol Eleonora Graziano, Alessandra Russo, Venera Cardile

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Sensory Perception of Six Essential Oils in Humans andMolecules (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Effect ofBiomolecules · 2025
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rosanna AvolaFaculty of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.ORCID 0000-0002-3094-2416
Alessandro Giuseppe FurnariDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Adriana Carol Eleonora GrazianoFaculty of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.
Alessandra RussoDepartment of Drug and Health Sciences, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-2925-6600
Venera CardileDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
University of Catania · ITUniversità degli Studi di Enna Kore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation, a pivotal factor in the pathogenesis of various brain disorders, including neurodegenerative diseases, has become a focal point for therapeutic exploration. This review highlights neuroinflammatory mechanisms that hallmark neurodegenerative diseases and the potential benefits of essential oils in counteracting neuroinflammation and oxidative stress, thereby offering a novel strategy for managing and mitigating the impact of various brain disorders. Essential oils, derived from aromatic plants, have emerged as versatile compounds with a myriad of health benefits. Essential oils exhibit robust antioxidant activity, serving as scavengers of free radicals and contributing to cellular defense against oxidative stress. Furthermore, essential oils showcase anti-inflammatory properties, modulating immune responses and mitigating inflammatory processes implicated in various chronic diseases. The intricate mechanisms by which essential oils and phytomolecules exert their anti-inflammatory and antioxidant effects were explored, shedding light on their multifaceted properties. Notably, we discussed their ability to modulate diverse pathways crucial in maintaining oxidative homeostasis and suppressing inflammatory responses, and their capacity to rescue cognitive deficits observed in preclinical models of neurotoxicity and neurodegenerative diseases.

Indexed as

antioxidantsessential oilsnatural compoundsneurodegenerative diseasesneuroinflammationoxidative stress

Identifiers

PMID38397776
PMCPMC10886016
OpenAlexW4391385727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.