Evidence map›Paper›PMID 38397694›Full record

SynthesisInternational journal of environmental research and public health2024

Benzene Exposure and Lung Cancer Risk: A Systematic Review and Meta-Analysis of Human Studies.

Manuela Chiavarini, Patrizia Rosignoli, Beatrice Sorbara, Irene Giacchetta, Roberto Fabiani

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Carcinogenic Industrial Air Emissions and Lung Cancer Risk in a Cohort of 440,000 Americans.American journal of respiratory and critical care medicine · 2025
    Article
  13. Poor People of Color Breathe Poor Air.Annals of the American Thoracic Society · 2025
    Article
  14. Review
  15. Article
  16. Assessment of Exposure to Benzene Among Gasoline Station Workers in Thailand: Risk Assessment Matrix Methods.International journal of environmental research and public health · 2025
    Article
  17. Review
  18. Review
  19. Occupational Benzene Exposure and Cancer Risk among Chinese Men: A Report from the Shanghai Men's Health Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Manuela ChiavariniDepartment of Biomedical Sciences and Public Health, Section of Hygiene, Preventive Medicine and Public Health, Polytechnic University of the Marche Region, 60126 Ancona, Italy.ORCID 0000-0002-3551-7486
Patrizia RosignoliDepartment of Chemistry, Biology and Biotechnology, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0002-8703-3248
Beatrice SorbaraDepartment of Chemistry, Biology and Biotechnology, University of Perugia, 06123 Perugia, Italy.
Irene GiacchettaDepartment of Medicine and Surgery, Section of Public Heath, School of Hygiene and Preventive Medicine, University of Perugia, 06123 Perugia, Italy.
Roberto FabianiDepartment of Biomedical Sciences and Public Health, Section of Hygiene, Preventive Medicine and Public Health, Polytechnic University of the Marche Region, 60126 Ancona, Italy.ORCID 0000-0003-4865-9413
University of Perugia · ITMarche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is a leading cause of death with nearly 1.8 million deaths estimated worldwide in 2020. Although benzene is classified as a human carcinogen (Group 1) on the basis of its association with acute myeloid/non-lymphocytic leukaemia, there is still limited evidence that it may influence lung cancer risk. This study examined the potential link between benzene exposure and risk of lung cancer using a systematic review of epidemiological studies and meta-analysis. We searched through PubMed, Web of Science and Scopus databases up to 10 February 2023 to identify all articles on the association between benzene exposure and lung cancer (incidence or prevalence) and/or mortality. We extracted the risk estimates of the highest and the lowest reported categories of benzene exposure and conducted a meta-analysis using a random-effects model. Heterogeneity and publication bias were analysed using an I

Indexed as

BenzeneLung NeoplasmsEnvironmental ExposureHumansRisk FactorsBenzenebenzeneincidencelung cancermeta-analysismortalityoccupational exposure

Identifiers

PMID38397694
PMCPMC10887806
OpenAlexW4391678671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.