Evidence map›Paper›PMID 38397456›Full record

ArticleBiomolecules2024

Discovery of A Novel Series of Quinazoline-Thiazole Hybrids as Potential Antiproliferative and Anti-Angiogenic Agents.

Alexandru Șandor, Ionel Fizeșan, Ioana Ionuț, Gabriel Marc, Cristina Moldovan, Ilioara Oniga, Adrian Pîrnău, Laurian Vlase, Andreea-Elena Petru, Ioana Macasoi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. New Quinazolin-4(3Molecules (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Alexandru ȘandorDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babes, Street, 400010 Cluj-Napoca, Romania.ORCID 0000-0003-0715-8372
Ionel FizeșanDepartment of Toxicology, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012 Cluj-Napoca, Romania.
Ioana IonuțDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babes, Street, 400010 Cluj-Napoca, Romania.
Gabriel MarcDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babes, Street, 400010 Cluj-Napoca, Romania.ORCID 0000-0001-9397-0388
Cristina MoldovanDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babes, Street, 400010 Cluj-Napoca, Romania.ORCID 0000-0002-5803-6108
Ilioara OnigaDepartment of Pharmacognosy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 12 Ion Creangă Street, 400010 Cluj-Napoca, Romania.ORCID 0000-0002-7660-9993
Adrian PîrnăuNational Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donath Street, 400293 Cluj-Napoca, Romania.ORCID 0000-0002-2313-9350
Laurian VlaseDepartment of Pharmaceutical Technology and Biopharmaceutics, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș, Street, 400012 Cluj-Napoca, Romania.ORCID 0000-0002-0664-3387
Andreea-Elena PetruDepartment of Toxicology, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012 Cluj-Napoca, Romania.ORCID 0000-0002-3149-9815
Ioana MacasoiDepartment of Toxicology, Faculty of Pharmacy, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania.ORCID 0000-0002-9890-2277
Ovidiu OnigaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babes, Street, 400010 Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · RONational Institute for Research and Development of Isotopic and Molecular Technologies · ROVictor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

"Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania PCD 881/45/12.01.2022 & 772/36/11.01.2023MCID through the "Nucleu" Program within the National Plan for Research, Development and Innovation 2022-2027 PN 23 24 01 05
6 · The paper itself

Abstract

Considering the pivotal role of angiogenesis in solid tumor progression, we developed a novel series of quinazoline-thiazole hybrids (

Indexed as

Antineoplastic AgentsAngiogenesis InhibitorsCell ProliferationMolecular Docking SimulationMolecular StructureProtein Kinase InhibitorsQuinazolinesSorafenibAngiogenesis InhibitorsAntineoplastic AgentsProtein Kinase InhibitorsQuinazolinesSorafenibanti-angiogenicantiproliferativecancerdrug discoveryhybrid compoundsquinazolinesmall moleculesstructure designsynthesisthiazoletyrosine kinase inhibitorsVEGFR2

Identifiers

PMID38397456
PMCPMC10886515
OpenAlexW4391753955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.