Evidence map›Paper›PMID 38397454›Full record

ArticleBiomolecules2024

Energy Metabolites and Indicative Significance of α-Ketoglutarate and α-Ketoglutaramate in Assessing the Progression of Chronic Hepatoencephalopathy.

Yevgeniya I Shurubor, Andrey B Krasnikov, Elena P Isakova, Yulia I Deryabina, Vladimir S Yudin, Anton A Keskinov, Boris F Krasnikov

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yevgeniya I ShuruborCentre for Strategic Planning of FMBA of Russia, Pogodinskaya St., Bld. 10, 119121 Moscow, Russia.ORCID 0000-0003-4060-3087
Andrey B KrasnikovIndependent Researcher, 24 Ivana Babushkina St., 117292 Moscow, Russia.
Elena P IsakovaBach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.
Yulia I DeryabinaBach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.
Vladimir S YudinCentre for Strategic Planning of FMBA of Russia, Pogodinskaya St., Bld. 10, 119121 Moscow, Russia.ORCID 0000-0002-9199-6258
Anton A KeskinovCentre for Strategic Planning of FMBA of Russia, Pogodinskaya St., Bld. 10, 119121 Moscow, Russia.
Boris F KrasnikovCentre for Strategic Planning of FMBA of Russia, Pogodinskaya St., Bld. 10, 119121 Moscow, Russia.ORCID 0000-0001-9525-4385
Center for Strategic Research · RUA N Bach Institute of Biochemistry · RUIndependent University of Moscow · RUPirogov Russian National Research Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the example of a rat model with chronic hepatoencephalopathy (HE), changes in the organ morphology of rats affect the balance of metabolites of the tricarboxylic acid (TCA) cycle and metabolites of the glutamine-glutamate (Gln-Glu) cycle, namely α-ketoglutarate (αKG) and α-ketoglutaramate (αKGM), as well as the enzymes associated with them, ω-amidase (ωA) and glutamine transaminase (GTK). This model of rats was obtained as a result of 2-22 weeks of consumption by animals of hepatotoxin thioacetamide (TAA) added to drinking water at a concentration of 0.4 g/L. The control (

Indexed as

GlutamineKetoglutaric AcidsAnimalsGlutamic AcidHumansLiverRatsalpha-ketoglutaramateGlutamic AcidGlutamineKetoglutaric Acidsglutamine transaminasehepatoencephalopathyHPLCthioacetamidetricarboxylic acid cycleα-ketoglutaramateα-ketoglutarateω-amidase

Identifiers

PMID38397454
PMCPMC10887089
OpenAlexW4391754041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.