Evidence map›Paper›PMID 38397446›Full record

ArticleBiomolecules2024

EEG Frequency Correlates with α

Adam F Kemp, Martin Kinnerup, Birger Johnsen, Steen Jakobsen, Adjmal Nahimi, Albert Gjedde

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. The Noradrenergic Brain in Parkinson's Disease.Current neurology and neuroscience reports · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Adam F KempDepartment of Nuclear Medicine, Odense University Hospital, 5000 Odense, Denmark.ORCID 0000-0002-5357-8733
Martin KinnerupDepartment of Clinical Medicine, Aarhus University, 8000 Aarhus, Denmark.
Birger JohnsenDepartment of Clinical Medicine, Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0002-6516-8010
Steen JakobsenDepartment of Clinical Medicine, Aarhus University, 8000 Aarhus, Denmark.
Adjmal NahimiClinical Memory Research Unit, Department of Clinical Sciences, 211 46 Malmö, Sweden.
Albert GjeddeDepartment of Clinical Medicine, Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0002-3756-7401
Aarhus University · DKOdense University Hospital · DKSkåne University Hospital · SEUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIncreased theta and delta power and decreased alpha and beta power, measured with quantitative electroencephalography (EEG), have been demonstrated to have utility for predicting the development of dementia in patients with Parkinson's disease (PD). Noradrenaline modulates cortical activity and optimizes cognitive processes. We claim that the loss of noradrenaline may explain cognitive impairment and the pathological slowing of EEG waves. Here, we test the relationship between the number of noradrenergic α

methodsWe included nineteen patients with PD and thirteen healthy control (HC) subjects in the study. We used positron emission tomography (PET) with [

resultsPD patients had higher power in the theta and delta bands compared to the HC volunteers. Patients' theta band power was inversely correlated with α

conclusionsThe findings support the claim that the loss or dysfunction of noradrenergic neurotransmission may relate to the parallel processes of cognitive decline and EEG slowing.

Indexed as

Cognitive DysfunctionParkinson DiseaseElectroencephalographyHumansNorepinephrineReceptors, AdrenergicNorepinephrineReceptors, AdrenergicdementiaEEGlocus coeruleusnoradrenalineParkinson’sα2 adrenoceptor

Identifiers

PMID38397446
PMCPMC10886955
OpenAlexW4391747414

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.