Evidence map›Paper›PMID 38397395›Full record

ReviewBiomolecules2024

Circular RNAs in Breast Cancer: An Update.

Haolin Bao, Jiehan Li, Qihang Zhao, Qingling Yang, Yi Xu

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Upregulation of a CircularInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Non-Coding RNAs in Breast Cancer: Diagnostic and Therapeutic Implications.International journal of molecular sciences · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Haolin BaoDepartment of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Jiehan LiDepartment of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Qihang ZhaoDepartment of Mammary Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Qingling YangAnhui Province Key Laboratory of Cancer Translational Medicine, Bengbu Medical University, Bengbu 233030, China.
Yi XuDepartment of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Second Affiliated Hospital of Harbin Medical University · CNBengbu Medical College · CNFirst Affiliated Hospital of Wenzhou Medical University · CN

Funding

Beijing Xisike Clinical Oncology Research Foundation Y-QL202201-0020Initiative Research Fund of Heilongjiang Postdoctoral Science FoundationKey Laboratory of Human Development and Disease Research, Guangxi Medical University, Education Department of Guangxi Zhuang Autonomous Region RTFY202301Opening Project of Anhui Province Key Laboratory of Translational Cancer Research, Bengbu Medical College KFKT202301Opening Project of Key Laboratory of Tumor Immunology and Pathology, Army Medical University, Ministry of Education 2022jsz801Opening Project of Shaanxi Provincial Key Laboratory of Infection and Immune Diseases 2023-KFMS-2Opening Project of Shanghai Key Laboratory of Molecular Imaging 18DZ2260400Opening Project of State Key Laboratory of Oncology in South China HN2023-02Shenzhen Science and Technology Program ZDSYS20210623092001003Thematic Research Support Scheme of State Key Laboratory of Liver Research, The University of Hong Kong SKLLR/TRSS/2022/08
6 · The paper itself

Abstract

Breast cancer (BC), characterized by high heterogeneity, is the most commonly reported malignancy among females across the globe. Every year, many BC patients die owing to delayed diagnosis and treatment. Increasing researches have indicated that aberrantly expressed circular RNAs (circRNAs) are implicated in the tumorigenesis and progression of various tumors, including BC. Hence, this article provides a summary of the biogenesis and functions of circRNAs, as well as an examination of how circRNAs regulate the progression of BC. Moreover, circRNAs have aroused incremental attention as potential diagnostic and prognostic biomarkers for BC. Exosomes enriched with circRNAs can be secreted into the tumor microenvironment to mediate intercellular communication, affecting the progression of BC. Detecting the expression levels of exosomal circRNAs may provide reference for BC diagnosis and prognosis prediction. Illuminating insights into the earlier diagnosis and better treatment regimens of BC will be potentially available following elucidation of deeper regulatory mechanisms of circRNAs in this malignancy.

Indexed as

Breast NeoplasmsBiological TransportCarcinogenesisCell CommunicationFemaleHumansRNA, CircularTumor MicroenvironmentRNA, Circularbiomarkerbreast cancercircular RNAexosometreatment

Identifiers

PMID38397395
PMCPMC10887059
OpenAlexW4391316000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.