Evidence map›Paper›PMID 38397289›Full record

ArticleChildren (Basel, Switzerland)2024

Effectiveness of a Spectacle Lens with a Specific Asymmetric Myopic Peripheral Defocus: 12-Month Results in a Spanish Population.

Miguel Ángel Sánchez-Tena, Jose Miguel Cleva, Cesar Villa-Collar, Marta Álvarez, Alicia Ruiz-Pomeda, Clara Martinez-Perez, Cristina Andreu-Vazquez, Eva Chamorro, Cristina Alvarez-Peregrina

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07394556 (Prospective Research on the Intervention of Myoless2.0 Effectiveness), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07394556 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Prospective Research on the Intervention of Myoless2.0 Effectiveness (PRIME) in Pediatric Population

Typeobservational_patient_registrySponsorIndizen Optical Technologies, S.L.U.Ran2026 to 2028Enrolled180ConditionsMyopia ProgressionArmsmyopia control lens
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Spectacle lenses for control of myopia progression in children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Review
  3. IMI-Interventions for Controlling Myopia Onset and Progression 2025.Investigative ophthalmology & visual science · 2025
    Review
  4. Childhood Myopia Part I: Contemporary Treatment Options.Investigative ophthalmology & visual science · 2025
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Miguel Ángel Sánchez-TenaDepartment of Optometry and Vision, Faculty of Optics and Optometry, Universidad Complutense de Madrid, 28037 Madrid, Spain.ORCID 0000-0002-2583-1789
Jose Miguel ClevaClinical Research Department, Indizen Optical Technologies, 28002 Madrid, Spain.ORCID 0000-0002-2908-6616
Cesar Villa-CollarFaculty of Biomedical and Health Science, Universidad Europea de Madrid, 28670 Madrid, Spain.ORCID 0000-0002-6743-8264
Marta ÁlvarezClinical Research Department, Indizen Optical Technologies, 28002 Madrid, Spain.
Alicia Ruiz-PomedaDepartment of Optometry and Vision, Faculty of Optics and Optometry, Universidad Complutense de Madrid, 28037 Madrid, Spain.ORCID 0000-0002-8318-5914
Clara Martinez-PerezISEC LISBOA-Instituto Superior de Educação e Ciências, 1750-179 Lisbon, Portugal.ORCID 0000-0002-0996-5007
Cristina Andreu-VazquezFaculty of Biomedical and Health Science, Universidad Europea de Madrid, 28670 Madrid, Spain.ORCID 0000-0002-7558-4325
Eva ChamorroClinical Research Department, Indizen Optical Technologies, 28002 Madrid, Spain.
Cristina Alvarez-PeregrinaDepartment of Optometry and Vision, Faculty of Optics and Optometry, Universidad Complutense de Madrid, 28037 Madrid, Spain.ORCID 0000-0003-1097-4581

Funding

Indizen Optical Technologies, 28002, Madrid MD7XDM6WV2H8
6 · The paper itself

Abstract

backgroundDifferent designs of ophthalmic lenses have been studied to control the progression of myopia in children. This study aims to evaluate the short-term efficacy of a new design of ophthalmic lens with asymmetric myopic peripheral defocus (MPDL) on myopia progression in children compared to a control group wearing a single-vision lens (SVL).

methodsChildren aged 5 to 12 with myopia up to -0.50 D, astigmatism and anisometropia under 1.50 D, and corrected visual acuity over 20/20 were randomized to either the study group (MPDL) or control group (SVL). The myopia progression was evaluated by measuring axial length (AL) growth (IOL Master; Zeiss) over a period of one year.

resultsNinety-two subjects were recruited. Forty-six children were randomly assigned to the control group, and 46 to the study group. In total, 83 children completed the clinical trial, with a mean age of 10.81 [9.53-11.92] years, among which 59.04% were female. After one year of treatment, there was less AL elongation in the study group compared to the control group (0.14 ± 0.14 mm vs. 0.23 ± 0.15 mm,

conclusionsThe MPDL significantly reduced the absolute growth of AL by 39% (

Indexed as

childrenefficacymyopiamyopic peripheral defocus lenses

Identifiers

PMID38397289
PMCPMC10887607

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.