Evidence map›Paper›PMID 38397276›Full record

ArticleChildren (Basel, Switzerland)2024

Managing Pediatric Asthma Exacerbations: The Role of Timely Systemic Corticosteroid Administration in Emergency Care Settings-A Multicentric Retrospective Study.

Luna Antonino, Eva Goossens, Josefien van Olmen, An Bael, Johan Hellinckx, Isabelle Van Ussel, An Wouters, Tijl Jonckheer, Tine Martens, Sascha Van Nuijs and 10 more

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Luna AntoninoLaboratory of Experimental Medicine and Pediatrics, Department of Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0009-0003-1828-3774
Eva GoossensCentre for Research and Innovation in Care, Department of Nursing Science and Midwifery, Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0003-3421-5256
Josefien van OlmenDepartment of Family Medicine and Population Health, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0001-9724-1887
An BaelDepartment of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium.
Johan HellinckxDepartment of Pediatrics, General Hospital Klina (AZ Klina), 2930 Brasschaat, Belgium.
Isabelle Van UsselDepartment of Pediatrics, General Hospital Voorkempen (AZ Voorkempen), 2390 Malle, Belgium.
An WoutersDepartment of Pediatrics, General Hospital Voorkempen (AZ Voorkempen), 2390 Malle, Belgium.
Tijl JonckheerDepartment of Pediatrics, GasthuisZusters Antwerp, 2610 Antwerp, Belgium.
Tine MartensDepartment of Pediatrics, GasthuisZusters Antwerp, 2610 Antwerp, Belgium.
Sascha Van NuijsDepartment of Pediatrics, GasthuisZusters Antwerp, 2610 Antwerp, Belgium.
Carolin Van RossemDepartment of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium.
Yentl DriesenDepartment of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium.
Nathalie JouretDepartment of Pediatric Pulmonology, Antwerp University Hospital, 2610 Antwerp, Belgium.
Eva Ter HaarDepartment of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium.ORCID 0000-0003-0663-9051
Sabine RozenbergDepartment of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium.
Els VanderschaegheDepartment of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium.
Susanne van SteijnDepartment of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium.
Stijn VerhulstLaboratory of Experimental Medicine and Pediatrics, Department of Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Kim Van HoorenbeeckLaboratory of Experimental Medicine and Pediatrics, Department of Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Antwerp Pediatric Asthma Network Consortium
Antwerp University Hospital · BEUniversity of Antwerp · BEProvince of Antwerp · BEAZ Klina · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsthma is the most prevalent chronic respiratory condition in children. An asthma exacerbation (AE) is a frequent reason for emergency department (ED) visits. An important step in the management of a moderate to severe AE is the administration of systemic corticosteroids (SCS) within 1 h after ED presentation. This study aimed to determine the timing of SCS administration and correlate this with the length of stay and oxygen therapy duration and to explore factors predicting timely administration.

methodsThis study used a retrospective multicenter observational design based on electronic medical records review. Children aged < 18 years, presenting to the ED with a moderate to severe AE were included.

results205 patients were included. Only 28 patients received SCS within 60 min after ED arrival. The median time to SCS administration was 169 min (Q

conclusionsThree in four children who presented with a moderate to severe AE at the ED did not receive SCS within the first hour. A prolonged timing of SCS administration correlated with a prolonged length of stay and extended need for oxygen support.

Indexed as

asthmaasthma exacerbationchildrencorticosteroidsemergency servicehospital

Identifiers

PMID38397276
PMCPMC10886780
OpenAlexW4391251659

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.