Evidence map›Paper›PMID 38397218›Full record

ArticleGenes2024

Identification of Candidate Genes and Pathways Linked to the Temperament Trait in Sheep.

Estefanía Romaniuk, Brenda Vera, Pablo Peraza, Gabriel Ciappesoni, Juan Pablo Damián, Elize Van Lier

Open access · goldAbstract read
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Unravelling Heterozygosity-Rich Regions in the Holstein Genome.Animals : an open access journal from MDPI · 2025
    Article
  4. Article
  5. Article
  6. Genomic Inbreeding and Runs of Homozygosity Analysis of Cashmere Goat.Animals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Estefanía RomaniukDepartamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Avda. Garzón 780, Montevideo 12900, Uruguay.
Brenda VeraSistema Ganadero Extensivo, Instituto Nacional de Investigación Agropecuaria, INIA Las Brujas, Ruta 48, km 10, Canelones 90200, Uruguay.
Pablo PerazaSistema Ganadero Extensivo, Instituto Nacional de Investigación Agropecuaria, INIA Las Brujas, Ruta 48, km 10, Canelones 90200, Uruguay.ORCID 0000-0001-6822-0307
Gabriel CiappesoniSistema Ganadero Extensivo, Instituto Nacional de Investigación Agropecuaria, INIA Las Brujas, Ruta 48, km 10, Canelones 90200, Uruguay.ORCID 0000-0002-0091-3956
Juan Pablo DamiánDepartamento de Biociencias Veterinarias, Facultad de Veterinaria, Universidad de la República, Ruta 8, km 18, Montevideo 13000, Uruguay.ORCID 0000-0001-8042-5743
Elize Van LierDepartamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Avda. Garzón 780, Montevideo 12900, Uruguay.ORCID 0000-0002-1510-0456
Instituto Nacional de Investigación Agropecuaria · UYUniversidad de la República de Uruguay · UY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temperament can be defined as the emotional variability among animals of the same species in response to the same stimulus, grouping animals by their reactivity as nervous, intermediate, or calm. Our goal was to identify genomic regions with the temperament phenotype measured by the Isolation Box Test (IBT) by single-step genome-wide association studies (ssGWAS). The database consisted of 4317 animals with temperament records, and 1697 genotyped animals with 38,268 effective Single Nucleotide Polymorphism (SNP) after quality control. We identified three genomic regions that explained the greatest percentage of the genetic variance, resulting in 25 SNP associated with candidate genes on chromosomes 6, 10, and 21. A total of nine candidate genes are reported for the temperament trait, which is:

Indexed as

Genome-Wide Association StudyTemperamentAnimalsGenomeGenotypePhenotypeSheepCAPN1GRID2ovis ariesPYMGssGWASSYT7

Identifiers

PMID38397218
PMCPMC10887918
OpenAlexW4391752631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.