A Cross-Sectional Study of Protein Changes Associated with Dementia in Non-Obese Weight Matched Women with and without Polycystic Ovary Syndrome.

Alexandra E Butler, Abu Saleh Md Moin, Thozhukat Sathyapalan, Stephen L Atkin

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

1.6field-weighted citation impact, top 18% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

Neurodegenerative Disease: From Molecular Basis to Therapy, 2nd Edition.International journal of molecular sciences · 2025
Article
Polycystic Ovary Syndrome and Ferroptosis: Following Ariadne's Thread.Biomedicines · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Alexandra E ButlerResearch Department, Royal College of Surgeons of Ireland, Busaiteen P.O. Box 15503, Bahrain.ORCID 0000-0002-5762-3917

Abu Saleh Md MoinResearch Department, Royal College of Surgeons of Ireland, Busaiteen P.O. Box 15503, Bahrain.

Thozhukat SathyapalanAcademic Endocrinology, Diabetes and Metabolism, Hull York Medical School, Hull HU6 7RU, UK.ORCID 0000-0003-3544-2231

Stephen L AtkinResearch Department, Royal College of Surgeons of Ireland, Busaiteen P.O. Box 15503, Bahrain.ORCID 0000-0002-5887-7257

Royal College of Surgeons in Ireland - Bahrain · BHHull York Medical School · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysregulated Alzheimer's disease (AD)-associated protein expression is reported in polycystic ovary syndrome (PCOS), paralleling the expression reported in type 2 diabetes (T2D). We hypothesized, however, that these proteins would not differ between women with non-obese and non-insulin resistant PCOS compared to matched control subjects. We measured plasma amyloid-related proteins levels (Amyloid-precursor protein (APP), alpha-synuclein (SNCA), amyloid P-component (APCS), Pappalysin (PAPPA), Microtubule-associated protein tau (MAPT), apolipoprotein E (apoE), apoE2, apoE3, apoE4, Serum amyloid A (SAA), Noggin (NOG) and apoA1) in weight and aged-matched non-obese PCOS (

Indexed as

DementiaDiabetes Mellitus, Type 2Insulin ResistancePolycystic Ovary SyndromeAgedApolipoproteins EBody Mass IndexCross-Sectional StudiesExtracellular Matrix ProteinsFemaleHumansObesityvon Willebrand FactorApolipoproteins EECM1 protein, humanExtracellular Matrix Proteinsvon Willebrand FactorAlzheimer’s diseaseamyloid-associated proteinsPCOSpolycystic ovary syndrome

Identifiers

PMID38397086

DOI10.3390/ijms25042409

PMCPMC10889209

OpenAlexW4391944575

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.