Evidence map›Paper›PMID 38397041›Full record

ArticleInternational journal of molecular sciences2024

Cisplatin Toxicity Causes Neutrophil-Mediated Inflammation in Zebrafish Larvae.

Barbara Nunes Padovani, Camila Morales Fénero, Lais Cavalieri Paredes, Mariana Abrantes do Amaral, Omar Domínguez-Amorocho, Marcella Cipelli, Juliana Moreira Mendonça Gomes, Eloisa Martins da Silva, Luísa Menezes Silva, Raquel de Souza Vieira and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Barbara Nunes PadovaniDepartment of Immunology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508000, Brazil.
Camila Morales FéneroDepartment of Microbiology and Environmental Toxicology, Biomedical Sciences, University of California Santa, Santa Cruz, CA 95064, USA.
Lais Cavalieri ParedesDepartment of Immunology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508000, Brazil.
Mariana Abrantes do AmaralNephrology Division, Department of Medicine, Federal University of Sao Paulo, São Paulo 04023062, Brazil.
Omar Domínguez-AmorochoDepartment of Immunology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508000, Brazil.
Marcella CipelliDepartment of Immunology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508000, Brazil.
Juliana Moreira Mendonça GomesDepartment of Developmental & Molecular Biology, Albert Einstein College of Medicine, New York, NY 10461, USA.
Eloisa Martins da SilvaNephrology Division, Department of Medicine, Federal University of Sao Paulo, São Paulo 04023062, Brazil.
Luísa Menezes SilvaDepartment of Immunology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508000, Brazil.
Raquel de Souza VieiraDepartment of Immunology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508000, Brazil.
Mariana Tominaga PereiraDepartment of Immunology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508000, Brazil.
Mario Costa CruzDepartment of Immunology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508000, Brazil.
Niels Olsen Saraiva CâmaraDepartment of Immunology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508000, Brazil.ORCID 0000-0001-5436-1248
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BRAlbert Einstein College of Medicine · USUniversity of California, Santa Cruz · US

Funding

UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Ameer Taha · 2015 to 2026
$26.0M
Training of Surgeons for Studies of the Tumor MicroenvironmentT32CA200561 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI MCAULIFFE, JOHN · 2015 to 2024
$2.7M
Coordenação de Aperfeicoamento de Pessoal de Nível Superior Financial Code 001.National Council for Scientific and Technological Development Financial Code 001.NCI NIH HHS T32 CA200561NIEHS NIH HHS P30 ES023513São Paulo Research Foundation FAPESP- grants n° 2017/05264-7, 2015/21644-9)
6 · The paper itself

Abstract

Cisplatin is an antineoplastic agent used to treat various tumors. In mammals, it can cause nephrotoxicity, tissue damage, and inflammation. The release of inflammatory mediators leads to the recruitment and infiltration of immune cells, particularly neutrophils, at the site of inflammation. Cisplatin is often used as an inducer of acute kidney injury (AKI) in experimental models, including zebrafish (

Indexed as

Acute Kidney InjuryCisplatinAnimalsCytokinesInflammationLarvaMammalsNeutrophilsZebrafishCisplatinCytokinesAKIDanio rerioneutrophil

Identifiers

PMID38397041
PMCPMC10889180
OpenAlexW4391927061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.