Evidence map›Paper›PMID 38397016›Full record

Observational studyInternational journal of molecular sciences2024

The Role of the Kinin System and the Effect of Des-Arginine

Fabian Edinger, Sophia Edinger, Götz Schmidt, Christian Koch, Michael Sander, Emmanuel Schneck

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fabian EdingerDepartment of Anesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital, Justus-Liebig-University, 35392 Giessen, Germany.ORCID 0000-0002-7149-9705
Sophia EdingerDepartment of Anesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital, Justus-Liebig-University, 35392 Giessen, Germany.
Götz SchmidtDepartment of Anesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital, Justus-Liebig-University, 35392 Giessen, Germany.ORCID 0000-0003-2346-4265
Christian KochDepartment of Anesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital, Justus-Liebig-University, 35392 Giessen, Germany.ORCID 0000-0002-2655-7363
Michael SanderDepartment of Anesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital, Justus-Liebig-University, 35392 Giessen, Germany.ORCID 0000-0003-1677-3609
Emmanuel SchneckDepartment of Anesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital, Justus-Liebig-University, 35392 Giessen, Germany.
Justus-Liebig-Universität Gießen · DE

Funding

University of Giessen JLU CAREER
6 · The paper itself

Abstract

The effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the coagulation system is not fully understood. SARS-CoV-2 penetrates cells through angiotensin-converting enzyme 2 (ACE2) receptors, leading to its downregulation. Des-arginine

Indexed as

COVID-19Angiotensin-Converting Enzyme 2AngiotensinsBradykininCritical IllnessHumansSARS-CoV-2Angiotensin-Converting Enzyme 2AngiotensinsBradykininangiotensin 2coagulopathyCOVID-19DA9Bdes-arginine9-bradykininmultiplaterotem

Identifiers

PMID38397016
PMCPMC10889556
OpenAlexW4391883478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.