Evidence map›Paper›PMID 38396988›Full record

ArticleInternational journal of molecular sciences2024

Antioxidant Efficacy of Hwangryunhaedok-tang through Nrf2 and AMPK Signaling Pathway against Neurological Disorders In Vivo and In Vitro.

Su-Jin Bae, Won-Yung Lee, Seon Been Bak, Seung Jin Lee, Su-Jin Hwang, Geun-Woo Kim, Byung-Soo Koo, Sun-Dong Park, Hye-Hyun Yoo, Choon-Ok Kim and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Mechanism of Inosine fromFoods (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Su-Jin BaeSchool of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.ORCID 0000-0001-8884-7940
Won-Yung LeeSchool of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Seon Been BakSchool of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Seung Jin LeeSchool of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Su-Jin HwangKorean Medicine (KM)-Application Center, Korea Institute of Oriental Medicine (KIOM), Daegu 41062, Republic of Korea.
Geun-Woo KimSchool of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Byung-Soo KooSchool of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Sun-Dong ParkSchool of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Hye-Hyun YooCollege of Pharmacy, Hanyang University, Ansan 1558, Republic of Korea.ORCID 0000-0001-8282-852X
Choon-Ok KimDepartment of Clinical Pharmacology and Clinical Trials Center, Severance Hospital, Yonsei University Health System, Seoul 03722, Republic of Korea.ORCID 0000-0002-2319-1108
Hyung Won KangCollege of Korean Medicine, Wonkwang University, Iksan 54538, Republic of Korea.
Tae-Woo OhKorean Medicine (KM)-Application Center, Korea Institute of Oriental Medicine (KIOM), Daegu 41062, Republic of Korea.ORCID 0000-0001-7184-6503
Young Woo KimSchool of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.ORCID 0000-0002-3323-7106
Dongguk University · KRKorea Institute of Oriental Medicine · KRHanyang University · KRSeverance Hospital · KRWonkwang University · KR

Funding

Korea Health Industry Development Institute HF20C0212Korea Health Industry Development Institute HF21C0061National Research Foundation of Korea 2021R1C1C1012018
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a representative cause of dementia and is caused by neuronal loss, leading to the accumulation of aberrant neuritic plaques and the formation of neurofibrillary tangles. Oxidative stress is involved in the impaired clearance of amyloid beta (Aβ), and Aβ-induced oxidative stress causes AD by inducing the formation of neurofibrillary tangles. Hwangryunhaedok-tang (HHT, Kracie K-09

Indexed as

Alzheimer DiseaseAntioxidantsPlant ExtractsAMP-Activated Protein KinasesAmyloid beta-PeptidesAnimalsMiceNF-E2-Related Factor 2Oxidative StressPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal TransductionAMP-Activated Protein KinasesAmyloid beta-PeptidesAntioxidantshwangryunhaedok-tangNF-E2-Related Factor 2Phosphatidylinositol 3-KinasesPlant ExtractsProto-Oncogene Proteins c-aktAlzheimer’s diseaseAMPKbaicaleinHwangryunhaedok-tangNrf2

Identifiers

PMID38396988
PMCPMC10889506
OpenAlexW4391840550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.