Evidence map›Paper›PMID 38396946›Full record

ReviewInternational journal of molecular sciences2024

Long Non-Coding RNAs: New Insights in Neurodegenerative Diseases.

Adithya K Anilkumar, Puneet Vij, Samantha Lopez, Sophia M Leslie, Kyle Doxtater, Mohammad Moshahid Khan, Murali M Yallapu, Subhash C Chauhan, Gladys E Maestre, Manish K Tripathi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Circadian rhythm lncRNABiochemistry and biophysics reports · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. LncRNAs Orchestrating Neuroinflammation: A Comprehensive Review.Cellular and molecular neurobiology · 2025
    Review
  15. Review
  16. Article
  17. Article
  18. Reciprocal Inhibitions of HRP and REC in a Coculture System.Archives of ophthalmology and optometry · 2025
    Article
  19. Review
  20. Long noncoding RNAs in ubiquitination, protein degradation, and human diseases.Biochimica et biophysica acta. Gene regulatory mechanisms · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Adithya K AnilkumarMedicine and Oncology, ISU, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.
Puneet VijDepartment of Pharmaceutical Sciences, St. John's University, Queens, NY 11439, USA.
Samantha LopezMedicine and Oncology, ISU, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.
Sophia M LeslieMedicine and Oncology, ISU, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.
Kyle DoxtaterMedicine and Oncology, ISU, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.
Mohammad Moshahid KhanDepartment of Neurology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0003-4679-294X
Murali M YallapuMedicine and Oncology, ISU, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.ORCID 0000-0002-0073-8828
Subhash C ChauhanMedicine and Oncology, ISU, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.
Gladys E MaestreDepartment of Neurosciences, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78550, USA.
Manish K TripathiMedicine and Oncology, ISU, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.
The University of Texas Rio Grande Valley · USSt. John's University · USUniversity of Tennessee Health Science Center · US

Funding

South Texas Alzheimer's Disease Research CenterP30AG066546 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Sudha Seshadri · 2021 to 2026
$24.0M
Integration of Socio-Spatial Data for Neighborhoods with Multi-omic profiles to Identify and Mitigate Factors Affecting Risk of ALzheimer's DiseaseDP1AG069870 · NIA · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI MAESTRE, GLADYS E. · 2020 to 2024
$3.6M
Role of lncRNA UCA1 in anoikis resistantce and colorectal cancer metastasisR16GM146696 · NIGMS · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI TRIPATHI, MANISH K · 2022 to 2025
$740k
NIA NIH HHS P30 AG066546NIGMS NIH HHS R16 GM146696
6 · The paper itself

Abstract

Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), are gradually becoming a burden to society. The adverse effects and mortality/morbidity rates associated with these NDDs are a cause of many healthcare concerns. The pathologic alterations of NDDs are related to mitochondrial dysfunction, oxidative stress, and inflammation, which further stimulate the progression of NDDs. Recently, long non-coding RNAs (lncRNAs) have attracted ample attention as critical mediators in the pathology of NDDs. However, there is a significant gap in understanding the biological function, molecular mechanisms, and potential importance of lncRNAs in NDDs. This review documents the current research on lncRNAs and their implications in NDDs. We further summarize the potential implication of lncRNAs to serve as novel therapeutic targets and biomarkers for patients with NDDs.

Indexed as

Alzheimer DiseaseAmyotrophic Lateral SclerosisNeurodegenerative DiseasesParkinson DiseaseRNA, Long NoncodingHumansRNA, Long NoncodingAlzheimer’s disease (AD)amyotrophic lateral sclerosis (ALS)biomarkerslong non-coding (Lnc) RNAsneurodegenerative diseases (NDDs)Parkinson’s disease (PD)

Identifiers

PMID38396946
PMCPMC10889599
OpenAlexW4391822642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.