Evidence map›Paper›PMID 38396905›Full record

ArticleInternational journal of molecular sciences2024

Reduced Glycolysis and Cytotoxicity in

Lorena Tuchscherr, Sindy Wendler, Rakesh Santhanam, Juliane Priese, Annett Reissig, Elke Müller, Rida Ali, Sylvia Müller, Bettina Löffler, Stefan Monecke and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Transcriptional Reprogramming ofInternational journal of molecular sciences · 2026
    Article
  2. Review
  3. Journal of bacteriology · 2025
    Article
  4. [The role ofLin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lorena TuchscherrInstitute of Medical Microbiology, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0002-9328-5302
Sindy WendlerInstitute of Medical Microbiology, Jena University Hospital, 07747 Jena, Germany.
Rakesh SanthanamSystems Biology and Bioinformatics Unit, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, 07745 Jena, Germany.
Juliane PrieseDepartment of Otorhinolaryngology, Jena University Hospital, 07747 Jena, Germany.
Annett ReissigLeibniz Institute of Photonic Technology (IPHT), 07745 Jena, Germany.
Elke MüllerLeibniz Institute of Photonic Technology (IPHT), 07745 Jena, Germany.
Rida AliInstitute of Medical Microbiology, Jena University Hospital, 07747 Jena, Germany.
Sylvia MüllerInstitute of Immunology, University Hospital Jena, 07743 Jena, Germany.
Bettina LöfflerInstitute of Medical Microbiology, Jena University Hospital, 07747 Jena, Germany.
Stefan MoneckeLeibniz Institute of Photonic Technology (IPHT), 07745 Jena, Germany.
Ralf EhrichtLeibniz Institute of Photonic Technology (IPHT), 07745 Jena, Germany.ORCID 0000-0002-6612-0043
Orlando Guntinas-LichiusDepartment of Otorhinolaryngology, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0001-9671-0784
Jena University Hospital · DELeibniz Institute of Photonic Technology · DELeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DE

Funding

Bundesministeriums für Bildung und Forschung zur Projektförderung (NABF) 01K12306 StopStphGrowthFederal Ministry of Education and Research ADA (13GW0456C); ResiCheck (13GW0422C)Federal Ministry of Education and Research MESINFLAME (01EC1901B)
6 · The paper itself

Abstract

Chronic rhinosinusitis (CRS) is a multifactorial infection of the nasal cavity and sinuses. In this study, nasal swabs from control donors (N = 128) and patients with CRS (N = 246) were analysed. Culture methods and metagenomics revealed no obvious differences in the composition of the bacterial communities between the two groups. However, at the functional level, several metabolic pathways were significantly enriched in the CRS group compared to the control group. Pathways such as carbohydrate transport metabolism, ATP synthesis, cofactors and vitamins, photosynthesis and transcription were highly enriched in CRS. In contrast, pathways related to lipid metabolism were more representative in the control microbiome. As

Indexed as

Paranasal SinusesRhinitisRhinosinusitisSinusitisStaphylococcal InfectionsChronic DiseaseHost AdaptationHumansStaphylococcus aureuschronic rhinosinusitismicrobiomeStaphylococcus aureus

Identifiers

PMID38396905
PMCPMC10888669
OpenAlexW4391785151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.