Evidence map›Paper›PMID 38396878›Full record

ArticleInternational journal of molecular sciences2024

Isolation and Identification of a Tibetan Pig Porcine Epidemic Diarrhoea Virus Strain and Its Biological Effects on IPEC-J2 Cells.

Mei Li, Meng Wang, Yao Xi, Shantong Qiu, Qiaoying Zeng, Yangyang Pan

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  4. Berberine alleviates enterotoxigenicFrontiers in nutrition · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mei LiCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Meng WangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Yao XiCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Shantong QiuCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Qiaoying ZengCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Yangyang PanCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Gansu Agricultural University · CN

Funding

Fuxi Foundation for Youth Talent at Gansu Agricultural University No. Gaufx-02Y10Innovative Talent Project of Gansu Province 2022LQTD59Outstanding Youth Fund of Gansu Province No. 20JR10RA561Scientific Research Foundation for the New Scholars, Gansu Agricultural University No. GSAU-RCZX201701
6 · The paper itself

Abstract

Porcine epidemic diarrhoea virus (PEDV) is a coronavirus that can cause severe watery diarrhoea in piglets, with high morbidity and mortality rates, seriously hindering the healthy development of the global swine industry. In this study, we isolated a strain of PEDV from Tibetan pigs and named it CH/GS/2022. Subsequently, we screened the apoptosis signals of PEDV-infected IPEC-J2 cells and studied the correlation between apoptosis signals and cell apoptosis. The results showed that different infections of PEDV induced different degrees of apoptosis in cells, and PEDV-induced cell apoptosis was dose-dependent. We then detected the expression of the p53, p38, JNK, Bax, and Bcl-2 genes in the apoptosis signal pathway. The results showed that 24 h after PEDV infection, the expression of the p53, p38, JNK, and Bax genes in IPEC-J2 cells increased significantly, while the expression of the Bcl-2 gene decreased significantly (

Indexed as

AnthracenesPorcine epidemic diarrhea virusAnimalsbcl-2-Associated X ProteinCell LineSwineTibetTumor Suppressor Protein p53Anthracenesbcl-2-Associated X ProteinpyrazolanthroneTumor Suppressor Protein p53apoptosisIPEC-J2porcine epidemic diarrhoea virussignalling pathway

Identifiers

PMID38396878
PMCPMC10889329
OpenAlexW4391753279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.