ArticleInternational journal of molecular sciences2024
Transcriptome Analysis and Metabolic Profiling Reveal the Key Regulatory Pathways in Drought Stress Responses and Recovery in Tomatoes.
Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- γ-Valerolactone Reprograms Tomato Metabolism to Enhance Seedling Growth.Metabolites · 2026Article
- Effects of Selenomethionine Supplementation on Tomato Fruit Quality and Yield Under Deficit Irrigation.International journal of molecular sciences · 2026Article
- Transcriptome analysis of safflower (Carthamus tinctorius L.) reveals the roles of osmotic adjustment and regulatory mechanisms in response to drought stress.BMC plant biology · 2026Article
- Physiological and transcriptomic analysis of cranberry (Frontiers in plant science · 2026Article
- Integrative Transcriptomic and Evolutionary Analysis of Drought and Heat Stress Responses inPlants (Basel, Switzerland) · 2025Article
- Integrated analyses reveal drought responsive microRNAs and their target genes in cucumber.BMC genomics · 2025Article
- Progress and Impacts of "Omics" Technologies in Understanding the Drought Response in Cassava: Adoption for Food Security in Africa.Plant-environment interactions (Hoboken, N.J.) · 2025Review
- Biochemical Responses of Atacama and Blesbok Sweet Potato (Plants (Basel, Switzerland) · 2025Article
- Combined effects of calcium sources and water restriction on fruit yield and quality of 'Ataulfo' and 'Kent' mangoes.Frontiers in plant science · 2025Article
- Deciphering Drought Resilience in Solanaceae Crops: Unraveling Molecular and Genetic Mechanisms.Biology · 2024Review
- Mediterranean Tomato Landraces Exhibit Genotype-Specific Transcriptomic Responses to Water Stress.Physiologia plantarumArticle
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Authors and funding
7 authors.
Funding
Abstract
Drought stress is a major abiotic factor affecting tomato production and fruit quality. However, the genes and metabolites associated with tomato responses to water deficiency and rehydration are poorly characterized. To identify the functional genes and key metabolic pathways underlying tomato responses to drought stress and recovery, drought-susceptible and drought-tolerant inbred lines underwent transcriptomic and metabolomic analyses. A total of 332 drought-responsive and 491 rehydration-responsive core genes were robustly differentially expressed in both genotypes. The drought-responsive and rehydration-responsive genes were mainly related to photosynthesis-antenna proteins, nitrogen metabolism, plant-pathogen interactions, and the MAPK signaling pathway. Various transcription factors, including homeobox-leucine zipper protein ATHB-12, NAC transcription factor 29, and heat stress transcription factor A-6b-like, may be vital for tomato responses to water status. Moreover, 24,30-dihydroxy-12(13)-enolupinol, caffeoyl hawthorn acid, adenosine 5'-monophosphate, and guanosine were the key metabolites identified in both genotypes under drought and recovery conditions. The combined transcriptomic and metabolomic analysis highlighted the importance of 38 genes involved in metabolic pathways, the biosynthesis of secondary metabolites, the biosynthesis of amino acids, and ABC transporters for tomato responses to water stress. Our results provide valuable clues regarding the molecular basis of drought tolerance and rehydration. The data presented herein may be relevant for genetically improving tomatoes to enhance drought tolerance.
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