Evidence map›Paper›PMID 38396832›Full record

ArticleInternational journal of molecular sciences2024

Reticulocyte Antioxidant Enzymes mRNA Levels versus Reticulocyte Maturity Indices in Hereditary Spherocytosis, β-Thalassemia and Sickle Cell Disease.

Daniela Melo, Fátima Ferreira, Maria José Teles, Graça Porto, Susana Coimbra, Susana Rocha, Alice Santos-Silva

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniela MeloUCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4051-401 Porto, Portugal.
Fátima FerreiraHematology Service, Centro Hospitalar e Universitário de São João, 4051-401 Porto, Portugal.
Maria José TelesClinical Pathology, Centro Hospitalar e Universitário de São João, 4051-401 Porto, Portugal.
Graça PortoImuno-Hemotherapy Service, Centro Hospitalar Universitário de Santo António, 4051-401 Porto, Portugal.ORCID 0000-0002-1923-4638
Susana CoimbraUCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4051-401 Porto, Portugal.ORCID 0000-0001-8411-8038
Susana RochaUCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4051-401 Porto, Portugal.ORCID 0000-0003-4196-2217
Alice Santos-SilvaUCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4051-401 Porto, Portugal.

Funding

FCT/ MCTES from the project of Associate Laboratory Institute for Health and Bioeconomy (i4HB) LA/P/0140/2020FCT/ MCTES, Research Unit on Applied Molecular Biosciences -UCIBIO UIDP/04378/2020Fundação para a Ciência e Tecnologia SFRH/BD/ 139622/2018
6 · The paper itself

Abstract

The antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and peroxiredoxin 2 (Prx2) are particularly important in erythroid cells. Reticulocytes and other erythroid precursors may adapt their biosynthetic mechanisms to cell defects or to changes in the bone marrow environment. Our aim was to perform a comparative study of the mRNA levels of

Indexed as

Anemia, Sickle Cellbeta-ThalassemiaSpherocytosis, HereditaryAntioxidantsHumansReticulocytesRNA, MessengerSuperoxide Dismutase-1AntioxidantsRNA, MessengerSuperoxide Dismutase-1antioxidant enzymeshereditary spherocytosisreticulocytesickle cell diseaseβ-thalassemia

Identifiers

PMID38396832
PMCPMC10889157

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.