Evidence map›Paper›PMID 38396715›Full record

ReviewInternational journal of molecular sciences2024

Managing Colorectal Cancer from Ethology to Interdisciplinary Treatment: The Gains and Challenges of Modern Medicine.

Monika Berbecka, Maciej Berbecki, Anna Maria Gliwa, Monika Szewc, Robert Sitarz

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Monika BerbeckaDepartment of Human Anatomy, Medical University of Lublin, 20-950 Lublin, Poland.
Maciej BerbeckiGeneral Surgery Ward, Independent Health Center in Kraśnik, 23-200 Kraśnik, Poland.
Anna Maria GliwaDepartment of Human Anatomy, Medical University of Lublin, 20-950 Lublin, Poland.
Monika SzewcDepartment of Human Anatomy, Medical University of Lublin, 20-950 Lublin, Poland.ORCID 0000-0001-8171-8505
Robert SitarzDepartment of Human Anatomy, Medical University of Lublin, 20-950 Lublin, Poland.ORCID 0000-0001-7267-9516
Medical University of Lublin · PL

Funding

Medical University of Lublin Grant No. DS200.
6 · The paper itself

Abstract

Colorectal cancer (CRC) is a common malignant tumor of the gastrointestinal tract, which has become a serious threat to human health worldwide. This article exhaustively reviews colorectal cancer's incidence and relevance, carcinogenesis molecular pathways, up-to-date treatment opportunities, prophylaxis, and screening program achievements, with attention paid to its regional variations and changes over time. This paper provides a concise overview of known CRC risk factors, including familial, hereditary, and environmental lifestyle-related risk factors. The authors take a closer look into CRC's molecular genetic pathways and the role of specific enzymes involved in carcinogenesis. Moreover, the role of the general practitioner and multidisciplinary approach in CRC treatment is summarized and highlighted based on recent recommendations and experience. This article gives a clear understanding and review of the gains and challenges of modern medicine towards CRC. The authors believe that understanding the current patterns of CRC and its revolution is imperative to the prospects of reducing its burden through cancer prevention and cancer-adjusted treatment.

Indexed as

Colorectal NeoplasmsCarcinogenesisEthologyHumansRisk Factorsbiomarkerscolorectal cancercyclooxygenaseepidemiologygenes polymorphismpreventionprophylaxisrisk factorsscreening

Identifiers

PMID38396715
PMCPMC10889298
OpenAlexW4391606948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.