Evidence map›Paper›PMID 38396704›Full record

ArticleInternational journal of molecular sciences2024

The Alarmin Triad-IL-25, IL-33, and TSLP-Serum Levels and Their Clinical Implications in Chronic Spontaneous Urticaria.

Carmen-Teodora Dobrican-Băruța, Diana Mihaela Deleanu, Ioana Adriana Muntean, Irena Nedelea, Radu-Gheorghe Bălan, Gabriela Adriana Filip, Lucia Maria Procopciuc

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

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  7. International journal of molecular sciences · 2025
    Article
  8. Review
  9. Exploring the Impact of IL-33 Gene Polymorphism (International journal of molecular sciences · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Carmen-Teodora Dobrican-BăruțaDepartment of Allergology and Immunology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj Napoca, Romania.ORCID 0000-0001-7147-5642
Diana Mihaela DeleanuDepartment of Allergology and Immunology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj Napoca, Romania.
Ioana Adriana MunteanDepartment of Allergology and Immunology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj Napoca, Romania.ORCID 0000-0002-1724-5915
Irena NedeleaDepartment of Allergology and Immunology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj Napoca, Romania.
Radu-Gheorghe BălanDepartment of Allergology and Immunology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj Napoca, Romania.
Gabriela Adriana FilipDepartment of Anatomy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.ORCID 0000-0002-7447-4925
Lucia Maria ProcopciucDepartment of Biochemistry, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania.ORCID 0000-0002-4738-5775
Iuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study delves into the critical role of alarmins in chronic spontaneous urticaria (CSU), focusing on their impact on disease severity and the quality of life (QoL) of patients. We investigated the alterations in alarmin levels in CSU patients and their correlations with the Urticaria Activity Score (UAS7) and the Dermatology Life Quality Index (DLQI). We analyzed serum levels of interleukin-25 (IL-25), interleukin-33 (IL-33), and thymic stromal lymphopoietin (TSLP) in 50 CSU patients, comparing these to 38 healthy controls. The study examined the relationship between alarmin levels and clinical outcomes, including disease severity and QoL. Elevated levels of IL-33 and TSLP in CSU patients (

Indexed as

Chronic UrticariaUrticariaAlarminsBiomarkersChronic DiseaseCytokinesHumansInterleukin-17Interleukin-33Quality of LifeThymic Stromal LymphopoietinAlarminsBiomarkersCytokinesIL25 protein, humanInterleukin-17Interleukin-33Thymic Stromal LymphopoietinalarminsCSUDLQIIL-25IL-33mast cellsskinTSLPUAS7urticaria

Identifiers

PMID38396704
PMCPMC10889490
OpenAlexW4391613756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.