Evidence map›Paper›PMID 38396693›Full record

ArticleInternational journal of molecular sciences2024

Preliminary Report on the Influence of Acute Inflammation on Adiponectin Levels in Older Inpatients with Different Nutritional Status.

Jakub Husejko, Marcin Gackowski, Jakub Wojtasik, Dominika Strzała, Maciej Pesta, Katarzyna Mądra-Gackowska, Jarosław Nuszkiewicz, Alina Woźniak, Mariusz Kozakiewicz, Kornelia Kędziora-Kornatowska

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jakub HusejkoDepartment of Geriatrics, Faculty of Health Science, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowska-Curie 9 Street, 85-094 Bydgoszcz, Poland.ORCID 0000-0002-9217-298X
Marcin GackowskiDepartment of Toxicology and Bromatology, Faculty of Pharmacy, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, A. Jurasza 2 Street, 85-089 Bydgoszcz, Poland.ORCID 0000-0001-9176-7108
Jakub WojtasikCentre for Statistical Analysis, Nicolaus Copernicus University in Toruń, Chopina 12/18 Street, 87-100 Toruń, Poland.
Dominika StrzałaDepartment of Geriatrics, Faculty of Health Science, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowska-Curie 9 Street, 85-094 Bydgoszcz, Poland.ORCID 0000-0001-6332-879X
Maciej PestaDepartment of Geriatrics, Faculty of Health Science, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowska-Curie 9 Street, 85-094 Bydgoszcz, Poland.ORCID 0009-0008-9391-6910
Katarzyna Mądra-GackowskaDepartment of Geriatrics, Faculty of Health Science, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowska-Curie 9 Street, 85-094 Bydgoszcz, Poland.ORCID 0000-0003-1208-0290
Jarosław NuszkiewiczDepartment of Medical Biology and Biochemistry, Faculty of Medicine, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Karłowicza 24 Street, 85-092 Bydgoszcz, Poland.ORCID 0000-0003-1378-5065
Alina WoźniakDepartment of Medical Biology and Biochemistry, Faculty of Medicine, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Karłowicza 24 Street, 85-092 Bydgoszcz, Poland.ORCID 0000-0002-4492-4796
Mariusz KozakiewiczDepartment of Geriatrics, Faculty of Health Science, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowska-Curie 9 Street, 85-094 Bydgoszcz, Poland.ORCID 0000-0002-6988-3038
Kornelia Kędziora-KornatowskaDepartment of Geriatrics, Faculty of Health Science, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowska-Curie 9 Street, 85-094 Bydgoszcz, Poland.
Nicolaus Copernicus University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation can be triggered by a variety of factors, including pathogens, damaged cells, and toxic compounds. It is a biological response of the immune system, which can be successfully assessed in clinical practice using some molecular substances. Because adiponectin, a hormone released by adipose tissue, influences the development of inflammation, its evaluation as a potential measure of inflammation in clinical practice is justified. In the present contribution, statistical comparison of adiponectin concentration and selected molecular substances recognized in clinical practice as measures of inflammation were utilized to demonstrate whether adipose tissue hormones, as exemplified by adiponectin, have the potential to act as a measure of rapidly changing inflammation when monitoring older hospitalized patients in the course of bacterial infection. The study showed no statistically significant differences in adiponectin levels depending on the rapidly changing inflammatory response in its early stage. Interestingly, the concentration of adiponectin is statistically significantly higher in malnourished patients than in people with normal nutritional levels, assessed based on the MNA. According to the results obtained, adiponectin is not an effective measure of acute inflammation in clinical practice. However, it may serve as a biomarker of malnutrition in senile individuals.

Indexed as

AdiponectinMalnutritionNutritional StatusAgedGeriatric AssessmentHumansInflammationInpatientsNutrition AssessmentAdiponectinadiponectinbacterial infectioninflammationmalnutritionMNAnutritional statusolder inpatientsoxidative stress in infection

Identifiers

PMID38396693
PMCPMC10889142
OpenAlexW4391614724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.