Evidence map›Paper›PMID 38396470›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Artificial Intelligence in Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) Data Analysis-Toward Retinal Metabolic Diagnostics.

Natalie Thiemann, Svenja Rebecca Sonntag, Marie Kreikenbohm, Giulia Böhmerle, Jessica Stagge, Salvatore Grisanti, Thomas Martinetz, Yoko Miura

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. AI-driven multimodal retinal imaging for early detection and risk stratification of vascular and neurodegenerative diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Natalie ThiemannInstitute for Neuro- and Bioinformatics, University of Lübeck, 23538 Lübeck, Germany.
Svenja Rebecca SonntagDepartment of Ophthalmology, University of Luebeck, University Hospital Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany.
Marie KreikenbohmDepartment of Ophthalmology, University of Luebeck, University Hospital Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany.
Giulia BöhmerleDepartment of Ophthalmology, University of Luebeck, University Hospital Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany.
Jessica StaggeDepartment of Ophthalmology, University of Luebeck, University Hospital Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany.
Salvatore GrisantiDepartment of Ophthalmology, University of Luebeck, University Hospital Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany.
Thomas MartinetzInstitute for Neuro- and Bioinformatics, University of Lübeck, 23538 Lübeck, Germany.
Yoko MiuraDepartment of Ophthalmology, University of Luebeck, University Hospital Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany.ORCID 0000-0003-1896-7634
University Hospital Schleswig-Holstein · DEUniversity of Lübeck · DE

Funding

Business Development and Technology Transfer Corporation of Schleswig-Holstein (WT.SH) 22021019
6 · The paper itself

Abstract

The purpose of this study was to investigate the possibility of implementing an artificial intelligence (AI) approach for the analysis of fluorescence lifetime imaging ophthalmoscopy (FLIO) data even with small data. FLIO data, including the fluorescence intensity and mean fluorescence lifetime (τm) of two spectral channels, as well as OCT-A data from 26 non-smokers and 28 smokers without systemic and ocular diseases were used. The analysis was performed with support vector machines (SVMs), a well-known AI method for small datasets, and compared with the results of convolutional neural networks (CNNs) and autoencoder networks. The SVM was the only tested AI method, which was able to distinguish τ

Indexed as

artificial intelligencefluorescence lifetime imaging ophthalmoscopyretinal metabolismsmall datasmokingsupport vector machine

Identifiers

PMID38396470
PMCPMC10888399
OpenAlexW4391882439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.