Evidence map›Paper›PMID 38396325›Full record

ArticleJournal of cellular and molecular medicine2024

IL-8 from CD248-expressing cancer-associated fibroblasts generates cisplatin resistance in non-small cell lung cancer.

Jieheng Wu, Qiaoling Zhang, Jiangwei Wu, Zeyang Yang, Xinlei Liu, Chunju Lou, Xuanyin Wang, Jiangying Peng, Jinyuan Zhang, Zhenling Shang and 9 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Jieheng WuDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.ORCID 0000-0003-4927-3897
Qiaoling ZhangDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Jiangwei WuDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Zeyang YangDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Xinlei LiuGuizhou Prenatal Diagnsis Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Chunju LouDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Xuanyin WangDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Jiangying PengDepartment of Pharmaceutical analysis, Zunyi Medical University, Zunyi, Guizhou, China.
Jinyuan ZhangSchool of Health Management, Guangzhou Medical University, Guangzhou, Guangdong, China.
Zhenling ShangDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Jing XiaoDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Nianxue WangDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Ruya ZhangDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Jinyao ZhouDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Yun WangKey Laboratory of Infectious Immune and Antibody Engineering of Guizhou Province, Engineering Research Center of Cellular Immunotherapy of Guizhou Province, School of Biology and Engineering, Guizhou Medical University, Guiyang, Guizhou, China.
Zuquan HuKey Laboratory of Infectious Immune and Antibody Engineering of Guizhou Province, Engineering Research Center of Cellular Immunotherapy of Guizhou Province, School of Biology and Engineering, Guizhou Medical University, Guiyang, Guizhou, China.
Rui ZhangDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Jian ZhangDepartment of Thoracic Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Zhu ZengDepartment of Immunology, Guizhou Medical University, Guiyang, Guizhou, China.
Guiyang Medical University · CN

Funding

Basic Research Program of Guizhou Provincial Department of Science and Technology Agency ZK [2021]-118Flexible Talent Introduction Project of Guizhou Medical University RN2021-GK045High-level Talent Startup Fund Project of Guizhou Medical University J2020-77National Natural Science Foundation of China 12132006National Natural Science Foundation of China 82160566National Natural Science Foundation of China Cultivation Program of Guizhou Medical University 20NSP002National Natural Science Foundation of China Cultivation Program of Guizhou Medical University 21NSFCP26
6 · The paper itself

Abstract

Chemotherapy-resistant non-small cell lung cancer (NSCLC) presents a substantial barrier to effective care. It is still unclear how cancer-associated fibroblasts (CAFs) contribute to NSCLC resistance to chemotherapy. Here, we found that CD248

Indexed as

Antineoplastic AgentsCancer-Associated FibroblastsCarcinoma, Non-Small-Cell LungDrug Resistance, NeoplasmInterleukin-8Lung NeoplasmsAnimalsAntigens, CDAntigens, NeoplasmCell Line, TumorCell ProliferationCisplatinHumansMiceNF-kappa BAntigens, CDAntigens, NeoplasmAntineoplastic AgentsCD248 protein, humanCD248 protein, mouseCisplatinInterleukin-8NF-kappa Bcancer-associated fibroblastsCD248chemoresistanceIL-8non-small cell lung cancer

Identifiers

PMID38396325
PMCPMC10891307
OpenAlexW4392133360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.