Evidence map›Paper›PMID 38396258›Full record

ArticleNature neuroscience2024

Dopamine projections to the basolateral amygdala drive the encoding of identity-specific reward memories.

Ana C Sias, Yousif Jafar, Caitlin M Goodpaster, Kathia Ramírez-Armenta, Tyler M Wrenn, Nicholas K Griffin, Keshav Patel, Alexander C Lamparelli, Melissa J Sharpe, Kate M Wassum

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Nature neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
19.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Review
  3. Neural basis of social hierarchy across species.Nature reviews. Neuroscience · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Altered amygdala and striatal responsivity and prediction error encoding of temporal reward dynamics in post-trauma psychopathology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  11. Article
  12. Article
  13. Dopamine Supports Reward Prediction to Shape Reward-Pursuit Strategy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  14. Review
  15. Article
  16. A lateralized pathway for associating nutrients with flavors.bioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ana C SiasDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.
Yousif JafarDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.
Caitlin M GoodpasterDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.
Kathia Ramírez-ArmentaDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.
Tyler M WrennDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.
Nicholas K GriffinDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.
Keshav PatelDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.
Alexander C LamparelliDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.
Melissa J SharpeDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-5375-2076
Kate M WassumDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, USA. kwassum@ucla.edu.ORCID http://orcid.org/0000-0002-2635-7433
University of California, Los Angeles · USThe University of Sydney · AU

Funding

UCLA Training Program in Translational Neuroscience of Drug Abuse (TNDA)T32DA024635 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LARA A. RAY, Kate M Wassum · 2008 to 2026
$6.2M
Basolateral Amygdala Rapid Glutamate Signaling During Reward Decision-MakingR01DA035443 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Kate M Wassum · 2013 to 2026
$5.7M
Cholinergic regulation of striatal neurochemistry in cue-triggered decision-makingR01MH106972 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI OSTLUND, SEAN BJORN · 2016 to 2020
$2.5M
Contribution of non-canonical dopamine pathways to model-based learningR01DA057084 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Melissa Sharpe, Kate M Wassum · 2023 to 2026
$2.5M
The role of the lateral hypothalamus in the balance of learning and behavior towards relevant stimuliR01DA054967 · NIDA · UNIVERSITY OF SYDNEY · PI Melissa Sharpe · 2022 to 2026
$1.5M
NIDA NIH HHS R01 DA035443NIDA NIH HHS R01 DA054967NIDA NIH HHS R01 DA057084NIDA NIH HHS T32 DA024635NIMH NIH HHS R01 MH106972
6 · The paper itself

Abstract

To make adaptive decisions, we build an internal model of the associative relationships in an environment and use it to make predictions and inferences about specific available outcomes. Detailed, identity-specific cue-reward memories are a core feature of such cognitive maps. Here we used fiber photometry, cell-type and pathway-specific optogenetic manipulation, Pavlovian cue-reward conditioning and decision-making tests in male and female rats, to reveal that ventral tegmental area dopamine (VTA

Indexed as

Basolateral Nuclear ComplexAnimalsCuesDopamineFemaleLearningMaleRatsReinforcement, PsychologyRewardDopamine

Identifiers

PMID38396258
PMCPMC11110430
OpenAlexW4392103876

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.