Evidence map›Paper›PMID 38396110›Full record

ArticleHormones (Athens, Greece)2024

Relationship between body adiposity parameters and insulin resistance: a preliminary study of surrogate markers in Japan.

Nanae Tanemura, Tetsuya Kubota, Naoto Kubota, Tsuyoshi Chiba

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Article in Hormones (Athens, Greece), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nanae TanemuraNational Institutes of Biomedical Innovation, Health and Nutrition, 3-17 Senriokashinmachi, Settsu, Osaka, 566-0002, Japan. n-tanemura@nibiohn.go.jp.ORCID http://orcid.org/0000-0002-1787-9571
Tetsuya KubotaNational Institutes of Biomedical Innovation, Health and Nutrition, 3-17 Senriokashinmachi, Settsu, Osaka, 566-0002, Japan.
Naoto KubotaDepartment of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Tsuyoshi ChibaNational Institutes of Biomedical Innovation, Health and Nutrition, 3-17 Senriokashinmachi, Settsu, Osaka, 566-0002, Japan.
National Institute of Biomedical Innovation, Health and Nutrition · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAccording to the Japan National Health and Nutrition Survey 2019, the proportion of people with prediabetes is estimated to be 27.3%. Western-style dietary habits can lead to obesity and a functional abnormality of the adipose tissue, which can cause insulin resistance and predispose one to diabetes. We examined the relationship between insulin resistance using body adiposity parameters as surrogate markers.

methodsThis study enrolled 248 healthy participants to determine the association of six body adiposity parameters, namely, body mass index (BMI), waist circumference (WC), visceral adiposity index (VAI), lipid accumulation product index (LAP), waist circumference-triglyceride index (WTI), and triglyceride (TG)/high-density lipoprotein (HDL) ratio with insulin resistance. Receiver operating characteristics curve analyses were performed to assess the accuracy of these parameters in identifying insulin resistance.

resultsThe data of the 248 participants (women 79 and men 169) were examined in this study. WC showed the highest accuracy in the obese women group (cut-off value: 89.8 with sensitivity: 0.900 and specificity: 0.522, AUC: 0.680) and men group (cut-off value: 90.0 with sensitivity: 0.862 and specificity: 0.508, AUC: 0.701). The TG/HDL ratio showed the highest accuracy in men with non-obesity (cut-off value: 0.8 with sensitivity: 0.857 and specificity: 0.649, AUC: 0.780).

conclusionApplication of this finding should be useful in the early screening of obesity in men with non-obesity, such as during regular health check-up with the TG/HDL ratio in addition to the usually used WC, to assess insulin resistance and prevent lifestyle-related diseases that can lead to cardiovascular events.

Indexed as

AdiposityBiomarkersBody Mass IndexInsulin ResistanceTriglyceridesWaist CircumferenceAdultAgedFemaleHumansJapanMaleMiddle AgedObesityBiomarkersTriglyceridesBody adiposity parametersHealth check-upInsulin resistanceMen with non-obesityObesitySurrogate marker

Identifiers

PMID38396110
OpenAlexW4392773506

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.