Evidence map›Paper›PMID 38396021›Full record

ArticleNature communications2024

Single-cell transcriptomics identifies the differentiation trajectory from inflammatory monocytes to pro-resolving macrophages in a mouse skin allergy model.

Kensuke Miyake, Junya Ito, Kazufusa Takahashi, Jun Nakabayashi, Frank Brombacher, Shigeyuki Shichino, Soichiro Yoshikawa, Sachiko Miyake, Hajime Karasuyama

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
  2. Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Macrophages and TGFB signaling regulate fibrosis in theAmerican journal of physiology. Renal physiology · 2026
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Kensuke MiyakeInflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan. miyake.mbch@tmd.ac.jp.ORCID 0000-0003-1149-3755
Junya ItoInflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Kazufusa TakahashiInflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Jun NakabayashiCollege of Liberal Arts and Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Frank BrombacherInstitute of Infectious Disease and Molecular Medicine, International Center for Genetic and Biotechnology Cape Town Component & University of Cape Town, Cape Town, South Africa.
Shigeyuki ShichinoDivision of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute of Biomedical Sciences, Tokyo University of Science, Noda, Japan.ORCID 0000-0002-1683-2448
Soichiro YoshikawaDepartment of Immunology, Juntendo University School of Medicine, Tokyo, Japan.
Sachiko MiyakeDepartment of Immunology, Juntendo University School of Medicine, Tokyo, Japan.
Hajime KarasuyamaInflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.ORCID 0000-0003-0689-0836
Tokyo Medical and Dental University · JPJuntendo University · JPTokyo University of Science · JPUniversity of Cape Town · ZA

Funding

Japan Agency for Medical Research and Development (AMED) JP21gm6210025MEXT | Japan Science and Technology Agency (JST) JPMJAX232IMEXT | Japan Science and Technology Agency (JST) JPMJSP2120MEXT | Japan Society for the Promotion of Science (JSPS) 23KJ0837Ministry of Education, Culture, Sports, Science and Technology (MEXT) 19H01025Ministry of Education, Culture, Sports, Science and Technology (MEXT) 22H02845Ministry of Education, Culture, Sports, Science and Technology (MEXT) 22K007115
6 · The paper itself

Abstract

Both monocytes and macrophages are heterogeneous populations. It was traditionally understood that Ly6C

Indexed as

Dermatitis, AtopicMonocytesAnimalsGene Expression ProfilingInflammationMacrophagesMiceMice, Inbred C57BL

Identifiers

PMID38396021
PMCPMC10891131
OpenAlexW4392099205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.