Evidence map›Paper›PMID 38395982›Full record

ArticleBMC chemistry2024

Vancomycin and nisin-modified magnetic Fe

Mona Nasaj, Abbas Farmany, Leili Shokoohizadeh, Farid Aziz Jalilian, Reza Mahjoub, Ghodratollah Roshanaei, Alireza Nourian, Omid Heydari Shayesteh, Mohammadreza Arabestani

Abstract read
In one paragraph

Article in BMC chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mona NasajDepartment of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Islamic Republic of Iran.
Abbas FarmanyDental Research Center, School of Dentistry, Hamadan University of Medical Sciences, Hamadan, Islamic Republic of Iran.
Leili ShokoohizadehDepartment of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Islamic Republic of Iran.
Farid Aziz JalilianDepartment of Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Shahid Fahmideh Street, Park Mardome, Hamadan, Islamic Republic of Iran.
Reza MahjoubDepartment of Pharmacology and Toxicology, School of Pharmacy, Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Islamic Republic of Iran.
Ghodratollah RoshanaeiDepartment of Biostatistics, School of Health, Hamadan University of Medical Sciences, Shahid Fahmideh Street, Park Mardome, Hamadan, Islamic Republic of Iran.
Alireza NourianDepartment of Pathobiology, School of Veterinary Science, Bu-Ali Sina University, Hamedan, Islamic Republic of Iran.
Omid Heydari ShayestehDepartment of Medicinal Chemistry, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Islamic Republic of Iran.
Mohammadreza ArabestaniDepartment of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Islamic Republic of Iran. mohammad.arabestani@gmail.com.

Funding

The vice chancellor for research and technology, Hamadan University of medical sciences, Hamadan/Iran 9808216062
6 · The paper itself

Abstract

backgroundThe objective of this research was to prepare some Fe

methodsIn this survey, the Fe

resultsBased on the XRD, and FE-SEM findings, the average size of the modified magnetic nanomaterials were estimated to be around 22-35 nm, and 34-47 nm, respectively. The vancomycin was conjugated in three polymer-drug ratios; 1:1, 2:1 and 3:1, with the percentages of 45.52%, 35.68%, and 24.4%, respectively. The polymer/drug ratio of 1:1 exhibited the slowest release rate of vancomycin from the Fe

conclusionThe vancomycin-functionalized nanocomposites exhibited to be more efficient in eradicating the bacterial cells both in vitro and in vivo. These findings introduce a novel bacteriocin-metallic nanocomposite that can suppress the normal bacterial function on demand for the treatment of MRSA skin infections.

Indexed as

Antibacterial activityChitosan-coated magnetic nanoparticleConjugation efficacyMRSANisinVancomycin

Identifiers

PMID38395982
PMCPMC10893753

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.