Evidence map›Paper›PMID 38395763›Full record

SynthesisBMC geriatrics2024

Dyslipidemia is associated with sarcopenia of the elderly: a meta-analysis.

Bingqing Bi, Xinying Dong, Meilin Yan, Zhuo Zhao, Ruitong Liu, Shugang Li, Hao Wu

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bingqing Bi *School of Public Health, Capital Medical University, Beijing, 100069, China.ORCID 0009-0005-2804-2477
Xinying Dong *School of Public Health, Capital Medical University, Beijing, 100069, China.
Meilin YanSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Zhuo ZhaoSchool of Public Health, Capital Medical University, Beijing, 100069, China.
Ruitong LiuSchool of Public Health, Capital Medical University, Beijing, 100069, China.
Shugang LiSchool of Public Health, Capital Medical University, Beijing, 100069, China. lishugang@ccmu.edu.cn.
Hao WuSchool of General Practice and Continuing Education, Capital Medical University, Beijing, 100069, China. wushunzhe@ccmu.edu.cn.
Capital Medical University · CN

Funding

Beijing High Level Public Health Technical Talents Training Plan 2022-1-005, Key Discipline Member-02-44
6 · The paper itself

Abstract

purposeSarcopenia is a pathological change characterized by muscle loss in older people. According to the reports, there is controversy on the relationship between dyslipidemia and sarcopenia. Therefore, this meta-analysis aimed to explore the association between sarcopenia and dyslipidemia.

methodsWe searched the Cochrane Library, Web of Science, PubMed, China National Knowledge Infrastructure (CNKI), Wan Fang, China Science and Technology Journal Database (VIP Database) for case‒control studies to extract data on the odds ratio (OR) between sarcopenia and dyslipidemia and the MD(mean difference) of TC, LDL-C, HDL-C, TG, and TG/HDL-C between sarcopenia and nonsarcopenia. The JBI(Joanna Briggs) guidelines were used to evaluate the quality. Excel 2021, Review Manager 5.3 and Stata 16.0 were used for the statistical analysis.

resultsTwenty studies were included in the meta-analysis, 19 of which were evaluated as good quality. The overall OR of the relationship between sarcopenia and dyslipidemia was 1.47, and the MD values of TC, LDL-C, HDL-C, TG, and TG/HDL-C were 1.10, 1.95, 1.27, 30.13, and 0.16 respectively. In female, compared with the non-sarcopnia, the MD of TC, LDL-C, HDL-C, TG of sarcopenia were - 1.67,2.21,1.02,-3.18 respectively. In male, the MD of TC, LDL-C, HDL-C, TG between sarcopenia and non-sarcopenia were - 0.51, 1.41, 5.77, -0.67. The OR between sarcopenia and dyslipidemia of the non-China region was 4.38, and it was 0.9 in China. In the group(> 60), MD of TC between sarcopenia and non-sarcopenia was 2.63, while it was 1.54 in the group(20-60).

conclusionDyslipidemia was associated with sarcopenia in the elderly, which was affected by sex, region and age.

Indexed as

DyslipidemiasSarcopeniaAgedFemaleHumansMaleDyslipidemiaHDL-CLDL-CSarcopeniaTCTG

Identifiers

PMID38395763
PMCPMC10885450
OpenAlexW4392109974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.