ArticleBMC geriatrics2024
Physical symptoms and anxiety and depression in older patients with advanced cancer in China: a network analysis.
Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Comparative efficacy of different exercise interventions for improving quality of life, depression, and anxiety in older adults with cancer: a systematic review and network meta-analysis.BMC geriatrics · 2026Pooled it
- Resilience in symptom response to cancer treatment: a new lens for examining variable symptom trajectories in older adults with advanced cancer.The oncologist · 2026Trial
- Analysis of the impact of dexmedetomidine on the vital signs of patients with anxiety at various time intervals upon entering the operating room.BMC psychiatry · 2025Trial
- A network analysis of benefit finding, posttraumatic growth, anxiety, and depression in breast cancer patients.Frontiers in oncology · 2026Article
- Mapping the Links Between Celebrity Worship and Subjective Well-Being in Chinese Undergraduates via Network Analysis.Behavioral sciences (Basel, Switzerland) · 2025Article
- Network analysis of multidimensional symptom experience among postoperative esophageal cancer survivors.Health and quality of life outcomes · 2025Article
- A validation study of the modified Chinese version of the integrated palliative care outcome scale (IPOS) among patients with advanced illness in Hong Kong.BMC palliative care · 2025Article
- Fear of cancer recurrence and influencing factors in elderly patients with gastric cancer undergoing laparoscopic radical surgery.World journal of gastrointestinal surgery · 2025Article
- Comparing EQ-5D-5L and IPOS among residents with malignant tumors in a community home hospice: a longitudinal study.BMC palliative care · 2025Article
- How mindfulness and coping styles shape anxiety and depression in metastatic gastrointestinal cancer.Frontiers in psychology · 2025Article
- Qualitative study on the evaluation of humanistic care quality in geriatric nursing based on three-dimensional quality structure theory.Frontiers in medicine · 2025Article
- Network Analysis of Contemporaneous Symptoms and Identification of Core Symptoms in Patients with Lumbar Disc Herniation.Journal of pain research · 2025Article
- Depression and Anxiety among Migrant Older Adults during the COVID-19 Pandemic in China: Network Analysis of Continuous Cross-Sectional Data.Healthcare (Basel, Switzerland) · 2024Article
- A study of the mediating effect of social support on self-disclosure and demoralization in Chinese older adult homebound breast cancer patients.Frontiers in psychology · 2024Article
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Authors and funding
23 authors at 11 institutions in 1 country.
Funding
Abstract
backgroundLittle is understood about the association between psychosomatic symptoms and advanced cancer among older Chinese patients.
methodsThis secondary analysis was part of a multicenter cross-sectional study based on an electronic patient-reported outcome platform. Patients with advanced cancer were included between August 2019 and December 2020 in China. Participants (over 60 years) completed the MD Anderson Symptom Inventory (MDASI) and Hospital Anxiety and Depression Scale (HADS) to measure symptom burden. Network analysis was also conducted to investigate the network structure, centrality indices (strength, closeness, and betweenness) and network stability.
resultsA total of 1022 patients with a mean age of 66 (60-88) years were included; 727 (71.1%) were males, and 295 (28.9%) were females. A total of 64.9% of older patients with advanced cancer had one or more symptoms, and up to 80% had anxiety and depression. The generated network indicated that the physical symptoms, anxiety and depression symptom communities were well connected with each other. Based on an evaluation of the centrality indices, 'distress/feeling upset' (MDASI 5) appears to be a structurally important node in all three networks, and 'I lost interest in my own appearance' (HADS-D4) had the lowest centrality indices. The network stability was relatively high (> 0.7).
conclusionThe symptom burden remains high in older patients with advanced cancer in China. Psychosomatic symptoms are highly interactive and often present as comorbidities. This network can be used to provide targeted interventions to optimize symptom management in older patients with advanced cancer in China.
trial registrationChinese Clinical Trial Registry (ChiCTR1900024957), registered on 06/12/2020.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.