Evidence map›Paper›PMID 38395706›Full record

ReviewTrends in cognitive sciences2024

The neurobiology of interoception and affect.

M J Feldman, E Bliss-Moreau, K A Lindquist

Abstract readReview
In one paragraph

Review in Trends in cognitive sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  5. Article
  6. Review
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  8. Review
  9. Putting Emotional Memories in Context: The Constructionist Model of Emotional Memory.Perspectives on psychological science : a journal of the Association for Psychological Science · 2026
    Review
  10. Review
  11. Article
  12. The priming effect of interoception on savoring positive emotion: An EEG study.Cognitive, affective & behavioral neuroscience · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

M J FeldmanDepartment of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: Mallory.Feldman@unc.edu.
E Bliss-MoreauDepartment of Psychology, University of California Davis, Davis, CA, USA; California National Primate Research Center, University of California Davis, Davis, CA, USA.
K A LindquistDepartment of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: kristen.lindquist@unc.edu.

Funding

An animal model of early Alzheimer’s disease pathogenesis in the interoceptive-allostatic networkRF1AG078340 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BLISS-MOREAU, ELIZA · 2022 to 2025
$3.9M
Development of a lifespan monkey model of interoceptionR21AG080198 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BLISS-MOREAU, ELIZA · 2023 to 2023
$434k
Age-related differences in neurobiological systems supporting emotionF31AG081073 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FELDMAN, MALLORY JEAN · 2023 to 2025
$122k
NIA NIH HHS F31 AG081073NIA NIH HHS R21 AG080198NIA NIH HHS RF1 AG078340
6 · The paper itself

Abstract

Scholars have argued for centuries that affective states involve interoception, or representations of the state of the body. Yet, we lack a mechanistic understanding of how signals from the body are transduced, transmitted, compressed, and integrated by the brains of humans to produce affective states. We suggest that to understand how the body contributes to affect, we first need to understand information flow through the nervous system's interoceptive pathways. We outline such a model and discuss how unique anatomical and physiological aspects of interoceptive pathways may give rise to the qualities of affective experiences in general and valence and arousal in particular. We conclude by considering implications and future directions for research on interoception, affect, emotions, and human mental experiences.

Indexed as

BrainInteroceptionAffectEmotionsHumansNeurobiologyaffectemotioninteroception

Identifiers

PMID38395706
PMCPMC11222051

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.