Evidence map›Paper›PMID 38395325›Full record

ArticleAmerican journal of ophthalmology2024

Socioeconomic Disparities in Glaucoma Severity at Initial Diagnosis: A Nationwide Electronic Health Record Cohort Analysis.

Swarup S Swaminathan, Felipe A Medeiros

Erratum issuedOpen access · greenAbstract readMulticenter Study
In one paragraph

Article in American journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Swarup S SwaminathanFrom the Bascom Palmer Eye Institute (S.S., F.M.), University of Miami Miller School of Medicine, Miami, Florida, USA. Electronic address: sswaminathan@miami.edu.
Felipe A MedeirosFrom the Bascom Palmer Eye Institute (S.S., F.M.), University of Miami Miller School of Medicine, Miami, Florida, USA.
University of Miami · US

Funding

The BCI (Brain Computer Interface) Glaucoma Study: Objective Home-Based Detection of Progressive Visual Function Loss in GlaucomaR01EY029885 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ASRANI, SANJAY, MEDEIROS, FELIPE · 2019 to 2022
$2.2M
Improving Individualized Assessments of Glaucoma Progression with Population-Based Electronic Health Record DataK23EY033831 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Swarup Sai Swaminathan · 2022 to 2026
$1.1M
Objective Quantification of Neural Damage for Screening, Diagnosis and Monitoring of Glaucoma with Fundus PhotographsR21EY031898 · NEI · DUKE UNIVERSITY · PI MEDEIROS, FELIPE · 2020 to 2021
$437k
NEI NIH HHS K23 EY033831NEI NIH HHS R01 EY029885NEI NIH HHS R21 EY031898
6 · The paper itself

Abstract

purposeTo assess disparities in initial disease severity among open-angle glaucoma (OAG) patients.

designCross-sectional study.

methodsIn this analysis of Epic Cosmos, an aggregated electronic health record dataset encompassing >213 million patients, OAG patients examined in ophthalmology or optometry clinics between January 1, 2013, and June 1, 2023, were evaluated. OAG severity at presentation was classified as mild, moderate, or severe using International Classification of Disease-10 codes. Demographics, social vulnerability index (SVI) scores, and rural-urban commuting area codes were evaluated as predictors of disease stage using ordinal logistic regression. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.

resultsOf 245,669 patients, 38.1% had mild, 32.5% moderate, and 29.3% severe disease at presentation. In multivariable analyses, significant determinants of worse severity included older age (OR: 1.23 per decade, 95% CI: 1.22-1.23), male sex (OR: 1.37, 95% CI: 1.35-1.39), Black race (OR: 1.61, 95% CI: 1.58-1.65), Hispanic ethnicity (OR: 1.15, 95% CI: 1.11-1.18), non-commercial insurance or uninsured status (OR: 2.53, 95% CI: 2.33-2.74), secondary OAGs (eg, pseudoexfoliative glaucoma - OR: 1.65, 95% CI: 1.58-1.72), and higher socioeconomic SVI scores (OR: 1.25 for highest versus lowest quartile, 95% CI: 1.22-1.28). Black and Hispanic patients were diagnosed at younger ages compared to White patients (mean ages: 67.8 ± 12.3 and 68.1 ± 12.8 vs 73.3 ± 11.8 years respectively, P < .001).

conclusionsWorse OAG at presentation was associated with older age, male sex, Black race, Hispanic ethnicity, non-commercial insurance or uninsured status, secondary OAGs, and greater socioeconomic vulnerability in this nationwide cohort. These findings can help tailor screening programs towards vulnerable populations.

Indexed as

Electronic Health RecordsGlaucoma, Open-AngleSeverity of Illness IndexSocioeconomic FactorsAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHealthcare DisparitiesHealth Status DisparitiesHumansIntraocular PressureMaleMiddle AgedOdds Ratio

Identifiers

PMID38395325
PMCPMC11162936
OpenAlexW4392059218

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.