Evidence map›Paper›PMID 38395086›Full record

ReviewInternational journal of radiation oncology, biology, physics2024

NRG Oncology and Particle Therapy Co-Operative Group Patterns of Practice Survey and Consensus Recommendations on Pencil-Beam Scanning Proton Stereotactic Body Radiation Therapy and Hypofractionated Radiation Therapy for Thoracic Malignancies.

Wei Liu, Hongying Feng, Paige A Taylor, Minglei Kang, Jiajian Shen, Jatinder Saini, Jun Zhou, Huan B Giap, Nathan Y Yu, Terence S Sio and 6 more

Abstract readReviewConsensus Statement
In one paragraph

Review in International journal of radiation oncology, biology, physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Wei LiuDepartment of Radiation Oncology, Mayo Clinic, Phoenix, Arizona. Electronic address: Liu.Wei@mayo.edu.
Hongying FengDepartment of Radiation Oncology, Mayo Clinic, Phoenix, Arizona; College of Mechanical and Power Engineering, China Three Gorges University, Yichang, Hubei, China; Department of Radiation Oncology, Guangzhou Concord Cancer Center, Guangzhou, Guangdong, China.
Paige A TaylorImaging and Radiation Oncology Core Houston Quality Assurance Center, University of Texas MD Anderson Cancer Center, Houston, Texas.
Minglei KangNew York Proton Center, New York City, New York.
Jiajian ShenDepartment of Radiation Oncology, Mayo Clinic, Phoenix, Arizona.
Jatinder SainiSeattle Cancer Care Alliance Proton Therapy Center and Department of Radiation Oncology, University of Washington School of Medicine, Seattle, Washington.
Jun ZhouDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia.
Huan B GiapDepartment of Radiation Oncology, Medical University of South Carolina, Charleston, South Carolina.
Nathan Y YuDepartment of Radiation Oncology, Mayo Clinic, Phoenix, Arizona.
Terence S SioDepartment of Radiation Oncology, Mayo Clinic, Phoenix, Arizona.
Pranshu MohindraDepartment of Radiation Oncology, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Joe Y ChangDepartment of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
Jeffrey D BradleyDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania.
Ying XiaoDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania.
Charles B SimoneNew York Proton Center, New York City, New York.
Liyong LinDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia.

Funding

NRG Oncology Network Group Operations Center - GY9 BIQSFP Reports/BudgetsU10CA180868 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI Quynh-Thu Xuan Le, ROBERT S. MANNEL · 2014 to 2026
$206.8M
IROC: Enhancing local enrolling site radiological data capture capabilities for NCTN trialsU24CA180803 · NCI · AMERICAN COLLEGE OF RADIOLOGY · PI Thomas J. FitzGerald, MICHAEL V KNOPP · 2014 to 2026
$116.2M
Network Lead Academic Participating Site: Memorial Sloan Kettering Cancer CenterUG1CA233290 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CAROL AGHAJANIAN, Darren Feldman · 2019 to 2026
$10.2M
4D Robust Optimization in Intensity-Modulated Proton TherapyK25CA168984 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LIU, WEI · 2012 to 2015
$450k
NCI NIH HHS K25 CA168984NCI NIH HHS U10 CA180868NCI NIH HHS U24 CA180803NCI NIH HHS UG1 CA233290
6 · The paper itself

Abstract

Stereotactic body radiation therapy (SBRT) and hypofractionation using pencil-beam scanning (PBS) proton therapy (PBSPT) is an attractive option for thoracic malignancies. Combining the advantages of target coverage conformity and critical organ sparing from both PBSPT and SBRT, this new delivery technique has great potential to improve the therapeutic ratio, particularly for tumors near critical organs. Safe and effective implementation of PBSPT SBRT/hypofractionation to treat thoracic malignancies is more challenging than the conventionally fractionated PBSPT because of concerns of amplified uncertainties at the larger dose per fraction. The NRG Oncology and Particle Therapy Cooperative Group Thoracic Subcommittee surveyed proton centers in the United States to identify practice patterns of thoracic PBSPT SBRT/hypofractionation. From these patterns, we present recommendations for future technical development of proton SBRT/hypofractionation for thoracic treatment. Among other points, the recommendations highlight the need for volumetric image guidance and multiple computed tomography-based robust optimization and robustness tools to minimize further the effect of uncertainties associated with respiratory motion. Advances in direct motion analysis techniques are urgently needed to supplement current motion management techniques.

Indexed as

Proton TherapyRadiation Dose HypofractionationRadiosurgeryThoracic NeoplasmsHumansLung NeoplasmsOrgans at RiskPractice Patterns, Physicians'Radiation OncologyRadiotherapy, Image-GuidedRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedUnited States

Identifiers

PMID38395086
PMCPMC11209785

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.