ArticleJournal of neurosurgery. Pediatrics2024
Multicenter comparison of Chiari malformation type I presentation in children versus adults.
Article in Journal of neurosurgery. Pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The symptom spectrum: preoperative symptom-related indicators of surgical outcomes for adult type 1 chiari malformation.Neurosurgical review · 2026Article
- Chiari malformation type I with extensive syringomyelia presenting as progressive bilateral foot drop: a case report.Korean journal of family medicine · 2025Article
- Difference in clinical presentation and surgical outcomes in pediatric and adult patients with Chiari malformation type 1: a single center retrospective study.Acta neurochirurgica · 2025Article
- Clinical efficacy of surgery for patients with Chiari malformation type I with syringomyelia: posterior fossa decompression versus posterior fossa decompression with resection of tonsils.Frontiers in neurology · 2025Article
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20 authors.
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Abstract
objectiveTreatment for Chiari malformation type I (CM-I) often includes surgical intervention in both pediatric and adult patients. The authors sought to investigate fundamental differences between these populations by analyzing data from pediatric and adult patients who required CM-I decompression.
methodsTo better understand the presentation and surgical outcomes of both groups of patients, retrospective data from 170 adults and 153 pediatric patients (2000-2019) at six institutions were analyzed.
resultsThe adult CM-I patient population requiring surgical intervention had a greater proportion of female patients than the pediatric population (p < 0.0001). Radiographic findings at initial clinical presentation showed a significantly greater incidence of syringomyelia (p < 0.0001) and scoliosis (p < 0.0001) in pediatric patients compared with adult patients with CM-I. However, presenting signs and symptoms such as headaches (p < 0.0001), ocular findings (p = 0.0147), and bulbar symptoms (p = 0.0057) were more common in the adult group. After suboccipital decompression procedures, 94.4% of pediatric patients reported symptomatic relief compared with 75% of adults with CM-I (p < 0.0001).
conclusionsHere, the authors present the first retrospective evaluation comparing adult and pediatric patients who underwent CM-I decompression. Their analysis reveals that pediatric and adult patients significantly differ in terms of demographics, radiographic findings, presentation of symptoms, surgical indications, and outcomes. These findings may indicate different clinical conditions or a distinct progression of the natural history of this complex disease process within each population, which will require prospective studies to better elucidate.
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