Evidence map›Paper›PMID 38394392›Full record

ReviewStem cells translational medicine2024

Recent Progress in Retinal Pigment Epithelium Cell-Based Therapy for Retinal Disease.

Valeriia Klymenko, Orlando G González Martínez, Marco Zarbin

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Stem cells translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Valeriia KlymenkoInstitute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Rutgers University, Newark, NJ, USA.
Orlando G González MartínezInstitute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Rutgers University, Newark, NJ, USA.ORCID 0000-0003-1326-2782
Marco ZarbinInstitute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Rutgers University, Newark, NJ, USA.
Rutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related macular degeneration and retinitis pigmentosa are degenerative retinal diseases that cause severe vision loss. Early clinical trials involving transplantation of retinal pigment epithelial cells and/or photoreceptors as a treatment for these conditions are underway. In this review, we summarize recent progress in the field of retinal pigment epithelium transplantation, including some pertinent clinical trial results as well as preclinical studies that address issues of transplant immunology, cell delivery, and cell manufacturing.

Indexed as

Macular DegenerationRetinal DiseasesHumansRetinaRetinal Pigment EpitheliumStem Cell Transplantationcell transplantationembryonic stem cellsgeographic atrophyinduced pluripotent stem cellsmacular degenerationretinaretinal pigment epitheliumretinitis pigmentosa

Identifiers

PMID38394392
PMCPMC11016854
OpenAlexW4392093020

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.