ArticleScience immunology2024
The gene regulatory basis of bystander activation in CD8
Open access · greenAbstract read
In one paragraph
Article in Science immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 36 citations in OpenAlex.
- Genetic background modifies host and viral parameters of neonatal gammaherpesvirus infection.Journal of virology · 2026Article
- Stress Hyperglycemia Drives CD4Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
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- The challenge and promise of studying human antigen-specific T cells.Nature reviews. Immunology · 2026Review
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- Perturbation of the preterm human immune system in early life.JCI insight · 2026Article
- Single-cell gene expression and TCR profiling reveal age-related differences in recent thymic emigrants.iScience · 2026Article
- Mapping Infant Immunity with Minimal Input: Integrative Single-cell and Multiomic Profiling.Journal of visualized experiments : JoVE · 2026Article
- Article
- Peripheral rotavirus-specific T-cell responses following monovalent oral rotavirus vaccine in infants.NPJ vaccines · 2026Article
- IL-4-STAT6 signaling delays protective CD8Nature immunology · 2026Article
- Divergent phenotypic and functional roles of human T follicular helper cells from infancy to adulthood.bioRxiv : the preprint server for biology · 2026Article
- T cell antigenic recognition sequencing (TAR-seq) enables precise characterization of vaccine-elicited cellular immunity ex vivo andFrontiers in immunology · 2026Article
- Developmental hematopoiesis: innate programming of αβ T cells.Experimental hematology · 2026Review
- LCMV-mediated loss of virtual memory CD8 T cells yields a functionally enhanced T cell subset.iScience · 2025Article
- An efficient framework to decipher microRNA regulatory programs applied to T cells.Genes and immunity · 2025Article
- Perturbation of the Preterm Human Immune System in Early Life.medRxiv : the preprint server for health sciences · 2025Article
- Article
- Early-life human CD8Proceedings of the National Academy of Sciences of the United States of America · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 5 institutions in 1 country.
Neva B WatsonDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA.ORCID 0009-0009-9378-5831
Ravi K PatelDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-5203-899X
Connor KeanDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-0132-1722
Janelle VeazeyDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-3061-0251
Oyebola O OyesolaDepartment of Immunology, University of Washington, Seattle, WA 98109, USA.ORCID 0000-0002-5347-7502
Nathan LaniewskiDavid H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Jennifer K GrenierGenomics Innovation Hub and TREx Facility, Institute of Biotechnology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-0928-7971
Jocelyn WangDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-0016-3136
Cybelle TabilasDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-5846-7269
Kristel J Yee MonDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-7355-4811
Adrian J McNairnGenomics Innovation Hub and TREx Facility, Institute of Biotechnology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-4727-3770
Seth A PengDepartment of Clinical Science, Cornell University, Ithaca, NY 14853, USA.
Samantha P WesnakDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-3445-7570
Kito NzinghaInstitute for Immunology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-8839-5208
Miles P DavenportKirby Institute for Infection and Immunity, UNSW Australia, Sydney, NSW 2052, Australia.ORCID 0000-0002-4751-1831
Elia D Tait WojnoDepartment of Immunology, University of Washington, Seattle, WA 98109, USA.ORCID 0000-0003-2822-296X
Kristin M ScheibleDepartment of Pediatrics, University of Rochester, Rochester, NY 14642, USA.
Norah L SmithDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-7495-7660
Andrew GrimsonDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-5794-6484
Brian D RuddDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-9742-8358
Cornell University · USUniversity of Washington · USUniversity of Pennsylvania · USUniversity of Rochester · USUniversity of Rochester Medical Center · US
Funding
Small RNA Pathways in Mammalian GametogenesisP50HD076210 · NICHD · CORNELL UNIVERSITY · PI SCHLEGEL, PETER N · 2014 to 2018
$7.4MThe developmental layers in the CD8+ T cell response to chronic infectionR01AI110613 · NIAID · CORNELL UNIVERSITY · PI GRIMSON, ANDREW W, RUDD, BRIAN DAVID · 2014 to 2022
$4.1MMechanisms Limiting Neonatal ImmunityR01AI105265 · NIAID · CORNELL UNIVERSITY · PI RUDD, BRIAN DAVID · 2014 to 2023
$4.0MRole of the prostaglandin D2 receptor CRTH2 in helminth-induced type 2 inflammation in the intestine.R01AI130379 · NIAID · UNIVERSITY OF WASHINGTON · PI Elia D Tait Wojno · 2017 to 2026
$3.5MRoles for DevelopmentallyRegulated microRNAs in Neonatal ImmunityU01AI131348 · NIAID · CORNELL UNIVERSITY · PI GRIMSON, ANDREW W, RUDD, BRIAN DAVID · 2017 to 2021
$2.2MProstaglandin D2 and its receptor CRTH2 regulate intestinal inflammation and homeostasisR01DK134410 · NIDDK · UNIVERSITY OF WASHINGTON · PI Elia D Tait Wojno · 2023 to 2026
$2.0MCD8 T Cell Dysregulation in Premature InfantsK08AI108870 · NIAID · UNIVERSITY OF ROCHESTER · PI SCHEIBLE, KRISTIN · 2014 to 2016
$539kDevelopmental layers in the CD8+ T cell response to infection.R21AI138025 · NIAID · CORNELL UNIVERSITY · PI SMITH, NORAH L · 2019 to 2020
$430kNIAID NIH HHS HHSN272201200005CNIAID NIH HHS K08 AI108870NIAID NIH HHS R01 AI105265NIAID NIH HHS R01 AI110613NIAID NIH HHS R01 AI130379NIAID NIH HHS R21 AI138025NIAID NIH HHS U01 AI131348NICHD NIH HHS P50 HD076210NIDDK NIH HHS R01 DK134410
Abstract
CD8
Indexed as
CD8-Positive T-LymphocytesImmunity, InnateAdultAnimalsAntigensCytokinesHumansMiceT-Lymphocyte SubsetsAntigensCytokines
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.