Evidence map›Paper›PMID 38393630›Full record

ReviewMolecular biotechnology2025

Recent Advances in the Role of Different Nanoparticles in the Various Biosensors for the Detection of the Chikungunya Virus.

Seyed Abbas Shahrtash, Zahraa Sabah Ghnim, Mohammad Ghaheri, Javid Adabi, Mohammad Amir Hassanzadeh, Saman Yasamineh, Hamed Afkhami, Amir Hossein Kheirkhah, Omid Gholizadeh, Hesam Zendehdel Moghadam

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 2 countries.

Seyed Abbas ShahrtashDepartment of Pharmaceutical Engineering, University of Tehran, Tehran, Iran.
Zahraa Sabah GhnimDepartment of Pharmacy, Al-Noor University College, Nineveh, Iraq.
Mohammad GhaheriStudent Research Committee, Alborz University of Medical Sciences, Karaj, Iran.
Javid AdabiChemical Engineering Department, Amirkabir University of Technology, Tehran, Iran.
Mohammad Amir HassanzadehDepartment of Microbiology, Zabol University of Medical Sciences, Zabol, Iran.
Saman YasaminehYoung Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
Hamed AfkhamiDepartment of Medical Microbiology, Faculty of Medicine, Shahed University of Medical Science, Tehran, Iran.
Amir Hossein KheirkhahDepartment of Tissue Engineering and Applied Cell Science, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
Omid GholizadehYoung Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran. ogholizade1374@gmail.com.ORCID http://orcid.org/0000-0002-2208-6437
Hesam Zendehdel MoghadamResearch Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran. dr.hesammoghadam@gmail.com.
Islamic Azad University of Tabriz · IRAl-Nisour University College · IQAmirkabir University of Technology · IRJahrom University of Medical Sciences · IRKerman University of Medical Sciences · IRQom University of Medical Science and Health Services · IRShahed University · IRUniversity of Tehran · IRZabol University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans contract the Chikungunya virus (CHIKV), an alphavirus transmitted by mosquitoes that induces acute and chronic musculoskeletal discomfort and fever. Millions of cases of the disease have been attributed to CHIKV in the Indian Ocean region since 2004, and the virus has since spread to Europe, the Middle East, and the Pacific. The exponential proliferation of CHIKV in recent times underscores the critical nature of implementing preventative measures and exploring potential control strategies. The principal laboratory test employed to diagnose infection in serum samples collected over six days after the onset of symptoms is the detection of CHIKV or viral RNA. Although two commercially available real-time reverse transcription-polymerase chain reaction products exist, data on their validity are limited. A diagnostic instrument that is rapid, sensitive, specific, and cost-effective is, therefore an absolute necessity, particularly in developing nations. Biosensors have demonstrated considerable potential in the realm of pathogen detection. The rapid and sensitive detection of viruses has been facilitated by the development of numerous types of biosensors, including affinity-based nano-biosensors, graphene affinity-based biosensors, optical nano-biosensors, surface Plasmon Resonance-based optical nano-biosensors, and electrochemical nano-biosensors. Furthermore, the utilization of nanomaterials for signal extension, including but not limited to gold and silver nanoparticles, quantum dots, and iron oxide NPs, has enhanced the precision and sensitivity of biosensors. The developed innovative diagnostic method is time-efficient, precise, and economical; it can be implemented as a point-of-care device. The technique may be implemented in diagnostic laboratories and hospitals to identify patients infected with CHIKV. Throughout this article, we have examined a multitude of CHIKV nano-biosensors and their respective properties. Following a discussion of representative nanotechnologies for biosensors, numerous NPs-assisted CHIKV nano-biosensors are summarized in this article. As a result, we anticipate that this review will furnish a significant foundation for advancing innovative CHIKV nano-biosensors.

Indexed as

Biosensing TechniquesChikungunya FeverChikungunya virusAnimalsHumansNanoparticlesRNA, ViralSurface Plasmon ResonanceRNA, ViralBiosensorChikungunya virusDetection methodsNanoparticlesRNA virus

Identifiers

PMID38393630
OpenAlexW4392111358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.