Evidence map›Paper›PMID 38393589›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Modeling Acute Myeloid Leukemia Using StarPEG-Heparin Hydrogels.

P Lewen Holloway, Akhilandeshwari Ravichandran, Julien Clegg, Claudia Bruedigam, Laura J Bray

Abstract read
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Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

P Lewen HollowaySchool of Mechanical, Medical and Process Engineering, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Akhilandeshwari RavichandranSchool of Mechanical, Medical and Process Engineering, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Julien CleggSchool of Mechanical, Medical and Process Engineering, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Claudia BruedigamCancer Program, Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute, Herston, QLD, Australia.
Laura J BraySchool of Mechanical, Medical and Process Engineering, Queensland University of Technology, Kelvin Grove, QLD, Australia. laura.bray@qut.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomimetic semi-synthetic hydrogels formed from a combination of star-shaped poly(ethylene glycol) (starPEG) and the glycosaminoglycan, heparin, allows for the three-dimensional (3D) culture of various cells and tissues. In this chapter, we describe methods for the use of starPEG-heparin hydrogels to cultivate primary and immortalized human acute myeloid leukemia (AML) cells. The resulting 3D culture models allow for the study of AML development and response to chemotherapeutic agents.

Indexed as

HeparinLeukemia, Myeloid, AcuteGlycosaminoglycansHumansHydrogelsPolyethylene GlycolsGlycosaminoglycansHeparinHydrogelsPolyethylene Glycols3D modelAcute myeloid leukemiaHydrogel

Identifiers

PMID38393589

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.