Evidence map›Paper›PMID 38393541›Full record

ArticleMagma (New York, N.Y.)2024

Impact of truncating diffusion MRI scans on diffusional kurtosis imaging.

Ana R Fouto, Rafael N Henriques, Marc Golub, Andreia C Freitas, Amparo Ruiz-Tagle, Inês Esteves, Raquel Gil-Gouveia, Nuno A Silva, Pedro Vilela, Patrícia Figueiredo and 1 more

Abstract read
In one paragraph

Article in Magma (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ana R FoutoInstitute for Systems and Robotics-Lisboa and Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal. anafouto@tecnico.ulisboa.pt.ORCID http://orcid.org/0000-0002-0362-9571
Rafael N HenriquesChampalimaud Research, Champalimaud Foundation, Lisbon, Portugal.
Marc GolubInstitute for Systems and Robotics-Lisboa and Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
Andreia C FreitasInstitute for Systems and Robotics-Lisboa and Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
Amparo Ruiz-TagleInstitute for Systems and Robotics-Lisboa and Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
Inês EstevesInstitute for Systems and Robotics-Lisboa and Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
Raquel Gil-GouveiaNeurology Department, Hospital da Luz, Lisbon, Portugal.
Nuno A SilvaLearning Health, Hospital da Luz, Lisbon, Portugal.
Pedro VilelaImaging Department, Hospital da Luz, Lisbon, Portugal.
Patrícia FigueiredoInstitute for Systems and Robotics-Lisboa and Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
Rita G NunesInstitute for Systems and Robotics-Lisboa and Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.

Funding

Fundação para a Ciência e a Tecnologia 2021.02777.CEECINDFundação para a Ciência e a Tecnologia COVID/BD/153268/2023Fundação para a Ciência e a Tecnologia PTDC/EMD-EMD/29675/2017Fundação para a Ciência e a Tecnologia SFRH/BD/139561/2018Fundação para a Ciência e a Tecnologia UIDB/50009/2020Programa Operacional Regional de Lisboa 2020 LISBOA-01-0145-FEDER-029675
6 · The paper itself

Abstract

objectiveDiffusional kurtosis imaging (DKI) extends diffusion tensor imaging (DTI), characterizing non-Gaussian diffusion effects but requires longer acquisition times. To ensure the robustness of DKI parameters, data acquisition ordering should be optimized allowing for scan interruptions or shortening. Three methodologies were used to examine how reduced diffusion MRI scans impact DKI histogram-metrics: 1) the electrostatic repulsion model (Opt MATERIALS AND

methodsPre-acquired diffusion multi-shell data from 14 female healthy volunteers (29±5 years) were used to generate reordered data. For each strategy, subsets containing different amounts of the full dataset were generated. The subsampling effects were assessed on histogram-based DKI metrics from tract-based spatial statistics (TBSS) skeletonized maps. To evaluate each subsampling method on simulated data at different SNRs and the influence of subsampling on in vivo data, we used a 3-way and 2-way repeated measures ANOVA, respectively.

resultsSimulations showed that subsampling had different effects depending on DKI parameter, with fractional anisotropy the most stable (up to 5% error) and radial kurtosis the least stable (up to 26% error). Random

conclusionThe impact of truncation depends on specific histogram-based DKI metrics. The use of a strategy for optimizing the acquisition order is advisable to improve DKI robustness to exam interruptions.

Indexed as

AlgorithmsBrainDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingHealthy VolunteersImage Processing, Computer-AssistedAdultAnisotropyComputer SimulationFemaleHumansImage Interpretation, Computer-AssistedReproducibility of ResultsSignal-To-Noise RatioDiffusional kurtosis imaging (DKI)Diffusion MRI (dMRI)Diffusion tensor imaging (DTI)Histogram-metricsSubsampling

Identifiers

PMID38393541
PMCPMC11452422

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.