Evidence map›Paper›PMID 38393470›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Artificial Modulation and Rewiring of Cell Cycle Progression Using Synthetic Circuits in Fission Yeast.

Akanksha Jain, Pei-Yun Jenny Wu, Damien Coudreuse

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Akanksha JainInstitute of Genetics and Development of Rennes, CNRS UMR 6290 and University of Rennes, Rennes, France.
Pei-Yun Jenny WuInstitute of Genetics and Development of Rennes, CNRS UMR 6290 and University of Rennes, Rennes, France.
Damien CoudreuseInstitute of Genetics and Development of Rennes, CNRS UMR 6290 and University of Rennes, Rennes, France. damien.coudreuse@ibgc.cnrs.fr.
Centre National de la Recherche Scientifique · FRInstitut de Biochimie et Génétique Cellulaires · FRInstitut de génétique et de développement de Rennes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell cycle control is a central aspect of the biology of proliferating eukaryotic cells. However, progression through the cell cycle relies on a highly complex network, making it difficult to unravel the core design principles underlying the mechanisms that sustain cell proliferation and the ways in which they interact with other cellular pathways. In this context, the use of a synthetic approach to simplify the cell cycle network in unicellular genetic models such as fission yeast has opened the door to studying the biology of proliferating cells from unique perspectives. Here, we provide a series of methods based on a minimal cell cycle module in the fission yeast Schizosaccharomyces pombe that allows for an unprecedented artificial control of cell cycle events, enabling the rewiring and remodeling of cell cycle progression.

Indexed as

SchizosaccharomycesSchizosaccharomyces pombe ProteinsCell CycleCell Cycle ProteinsCell DivisionCell Cycle ProteinsSchizosaccharomyces pombe ProteinsArtificial cell cycleCell cycle rewiringCyclin-dependent kinaseFission yeastMinimal cell cycle networkSynthetic cell cycle

Identifiers

PMID38393470
OpenAlexW4392105994

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.