Evidence map›Paper›PMID 38393348›Full record

ArticleWiener klinische Wochenschrift2024

[Cell-based influenza vaccines: an effective vaccine option for under 60-year-olds].

Barbara C Gärtner, Dietmar Beier, Gunther Gosch, Klaus Wahle, Luise Wendt, Laura-Christin Förster, Kim J Schmidt, Tino F Schwarz

Abstract readEnglish Abstract
In one paragraph

Article in Wiener klinische Wochenschrift, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Barbara C GärtnerInstitut für Medizinische Mikrobiologie und Hygiene, Universitätsklinikum des Saarlandes, Homburg/Saar, Deutschland.
Dietmar BeierSächsische Impfkommission, Chemnitz, Deutschland.
Gunther GoschKinderarztpraxis am Domplatz, Magdeburg, Deutschland.
Klaus WahleMedizinische Fakultät, Universität Münster, Münster, Deutschland.
Luise Wendtias-Gruppe, Leipzig, Deutschland.
Laura-Christin FörsterCSL Seqirus GmbH, München, Deutschland.
Kim J SchmidtXcenda GmbH, Hannover, Deutschland.
Tino F SchwarzInstitut für Labormedizin und Impfzentrum, Klinikum Würzburg Mitte, Standort Juliusspital, Salvatorstr. 7, 97074, Würzburg, Deutschland. tino.schwarz@kwm-klinikum.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The population < 60 years of age is also affected by a significant disease burden from seasonal influenza. It carries a high economic burden, mainly driven by influenza-associated productivity losses in the working population. Conventional egg-based influenza vaccines may experience reduced effectiveness due to antigen adaptation in eggs. In contrast, cell-based influenza vaccines are less likely to be affected by antigenic adaptations to the host system and showed better effectiveness in individuals 4-64 years old over several seasons compared to conventional egg-based influenza vaccines under real-world conditions. Preferential use of cell-based influenza vaccines, as opposed to conventional egg-based vaccines, could reduce the burden of influenza-related symptoms on individuals and alleviate the economic impact on the German population < 60 years of age.

Indexed as

Influenza, HumanInfluenza VaccinesAdolescentAdultChildChild, PreschoolCost of IllnessHumansMiddle AgedSeasonsVaccinationYoung AdultInfluenza VaccinesEgg adaptationEnhanced influenza vaccineInfluenzaReal-world dataVaccination recommendation

Identifiers

PMID38393348
PMCPMC10891230

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.