Evidence map›Paper›PMID 38393255›Full record

ArticleToxics2024

Embryotoxic Effects of Pesticides in Zebrafish (

Júlia Robert de Sousa Teixeira, Augusto Monteiro de Souza, João Vitor de Macedo-Sampaio, Fabiano Peres Menezes, Bruno Fiorelini Pereira, Silvia Regina Batistuzzo de Medeiros, Ana Carolina Luchiari

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  7. Pyriproxyfen, villain or good guy? A brief review.Archives of endocrinology and metabolism · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Júlia Robert de Sousa TeixeiraDepartment of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal 59072-970, RN, Brazil.
Augusto Monteiro de SouzaDepartment of Cell Biology and Genetics, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59072-970, RN, Brazil.
João Vitor de Macedo-SampaioDepartment of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal 59072-970, RN, Brazil.
Fabiano Peres MenezesBrazilian Institute of Environment and Renewable Natural Resources (IBAMA), Rio Grande 96200-180, RS, Brazil.ORCID 0000-0003-3996-0482
Bruno Fiorelini PereiraDepartment of Biology, Federal University of São Paulo (UNIFESP), Diadema 09913-030, SP, Brazil.ORCID 0000-0003-0416-7281
Silvia Regina Batistuzzo de MedeirosDepartment of Cell Biology and Genetics, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59072-970, RN, Brazil.
Ana Carolina LuchiariDepartment of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal 59072-970, RN, Brazil.
Universidade Federal do Rio Grande do Norte · BRBrazilian Institute of Environment and Renewable Natural Resources · BRUniversidade Federal de São Paulo · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior not applicableFundação de Amparo à Pesquisa do Estado de São Paulo 2022/03094-5National Council for Scientific and Technological Development 308245/2023-7
6 · The paper itself

Abstract

Diflubenzuron (DFB) and pyriproxyfen (PPF) are larvicides used in crops to control insect plagues. However, these pesticides are known to impact non-target organisms like fish and mammals. Here, we aimed at assessing the embryotoxicity of purified DFB, PPF, and their mixtures in a non-target organism-zebrafish. Zebrafish embryos were exposed to different concentrations for 120 h: 0.025, 0.125, 0.25, 1.25, 2.5, and 10 mg/L of purified PPF and purified DFB, while we used 0.025 mg/L PPF + 10 mg/L DFB (Mix A), 0.125 mg/L PPF + 10 mg/L DFB (Mix B), and 0.25 mg/L PPF + 10 mg/L DFB (Mix C) for the mixtures of PPF + DFB. We observed mortality, teratogenicity, and cardiotoxicity. For the neurotoxicity tests and evaluation of reactive oxygen species (ROS) levels in the brain, embryos were exposed for 120 h to 0.379 and 0.754 mg/L of PPF and 0.025 and 0.125 mg/L of DFB. We established the LC

Indexed as

agrochemicalbehaviormortalityneurotoxicityteratogenicity

Identifiers

PMID38393255
PMCPMC10892354
OpenAlexW4391942014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.