Evidence map›Paper›PMID 38393135›Full record

ArticleTropical medicine and infectious disease2024

Genomic and Phylogenetic Characterisation of SARS-CoV-2 Genomes Isolated in Patients from Lambayeque Region, Peru.

Sergio Luis Aguilar-Martinez, Gustavo Adolfo Sandoval-Peña, José Arturo Molina-Mora, Pablo Tsukayama-Cisneros, Cristian Díaz-Vélez, Franklin Rómulo Aguilar-Gamboa, D Katterine Bonilla-Aldana, Alfonso J Rodriguez-Morales

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Sergio Luis Aguilar-MartinezGrupo de Investigación en Bioinformática y Biología Estructural, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Lima 15081, Peru.
Gustavo Adolfo Sandoval-PeñaGrupo de Investigación en Bioinformática y Biología Estructural, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Lima 15081, Peru.ORCID 0000-0002-8392-9880
José Arturo Molina-MoraCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San Jose 11501-2060, Costa Rica.ORCID 0000-0001-9764-4192
Pablo Tsukayama-CisnerosFacultad de Ciencias e Ingeniería, Universidad Peruana Cayetano Heredia, Lima 15102, Peru.ORCID 0000-0002-1669-2553
Cristian Díaz-VélezFacultad de Medicina, Universidad Privada Antenor Orrego, Trujillo 13008, Peru.ORCID 0000-0003-4593-2509
Franklin Rómulo Aguilar-GamboaGrupo de Investigación en Inmunología y Virología del Norte, Laboratorio de Inmunología y Virología, Hospital Regional Lambayeque, Lambayeque 14011, Peru.ORCID 0000-0003-1943-5613
D Katterine Bonilla-AldanaResearch Unit, Universidad Continental, Huancayo 12001, Peru.ORCID 0000-0002-9412-2556
Alfonso J Rodriguez-MoralesFaculty of Health Sciences, Universidad Científica del Sur, Lima 15307, Peru.ORCID 0000-0001-9773-2192
National University of San Marcos · PEAntenor Orrego Private University · PEUniversidad Científica del Sur · PEUniversidad Continental · PEUniversidad de Costa Rica · CRUniversidad de Lambayeque · PEUniversidad Peruana Cayetano Heredia · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivethis study aims to identify and characterise genomic and phylogenetically isolated SARS-CoV-2 viral isolates in patients from Lambayeque, Peru.

methodsNasopharyngeal swabs were taken from patients from the Almanzor Aguinaga Asenjo Hospital, Chiclayo, Lambayeque, Peru, which had been considered mild, moderate, and severe cases of COVID-19. Patients had to have tested positive for COVID-19, using a positive RT-PCR for SARS-CoV-2. Subsequently, the SARS-CoV-2 complete viral genome sequencing was carried out using Illumina MiSeq

resultsIt was determined that during the period from December 2020 to January 2021, the lineages s C.14, C.33, B.1.1.485, B.1.1, B.1.1.1, and B.1.111 circulated, with lineage C.14 being the most predominant at 76.7% (n = 23/30). These lineages were classified in clade 20D mainly and also within clades 20B and 20A. On the contrary, the variants found in the second batch of samples of the period from September to October 2021 were Delta (72.7%), Gamma (13.6%), Mu (4.6%), and Lambda (9.1%), distributed between clades 20J, 21G, 21H, 21J, and 21I.

conclusionsThis study reveals updated information on the viral genomics of SARS-CoV-2 in the Lambayeque region, Peru, which is crucial to understanding the origins and dispersion of the virus and provides information on viral pathogenicity, transmission and epidemiology.

Indexed as

genomePeruphylogenetic analysisSARS-CoV-2sequencing

Identifiers

PMID38393135
PMCPMC10892787
OpenAlexW4391753449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.