Evidence map›Paper›PMID 38393075›Full record

ArticleVeterinary sciences2024

Modulation of Immune Response and Cecal Microbiota by Dietary Fenugreek Seeds in Broilers.

Deependra Paneru, Guillermo Tellez-Isaias, Walter G Bottje, Emmanuel Asiamah, Ahmed A A Abdel-Wareth, Md Salahuddin, Jayant Lohakare

Abstract read
In one paragraph

Article in Veterinary sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deependra PaneruDepartment of Poultry Science, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0002-2780-3933
Guillermo Tellez-IsaiasCenter of Excellence in Poultry Science, Division of Agriculture, University of Arkansas, Fayetteville, AR 72701, USA.ORCID 0000-0002-2416-2747
Walter G BottjeCenter of Excellence in Poultry Science, Division of Agriculture, University of Arkansas, Fayetteville, AR 72701, USA.
Emmanuel AsiamahDepartment of Agriculture, University of Arkansas at Pine Bluff, Pine Bluff, AR 71601, USA.
Ahmed A A Abdel-WarethDepartment of Animal and Poultry Production, Faculty of Agriculture, South Valley University, Qena 83523, Egypt.ORCID 0000-0001-5886-0415
Md SalahuddinPoultry Center, Cooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX 77446, USA.ORCID 0000-0003-0268-1084
Jayant LohakarePoultry Center, Cooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX 77446, USA.ORCID 0000-0001-5645-3007

Funding

United States Department of Agriculture 2019-69012-29905
6 · The paper itself

Abstract

Fenugreek seeds (FSs) are a natural source of bioactive compounds that may modulate the immune system and gut microbiota in broilers. This study examined the effects of dietary fenugreek seed powder on immune-related gene expression and cecal microbiota composition in broilers. A total of 144 broiler chickens were randomly allocated to three dietary groups, CON (0 g/kg FS, FS5 (5 g/kg FS) and FS10 (10 g/kg FS), each with 6 replicates of 8 birds. Ileum tissues and cecal contents were collected on day 42 for the mRNA expression of inflammation and antimicrobial defense-related genes and cecal microbiome diversity, respectively. The results indicated that fenugreek seeds downregulated mRNA-level inflammation and antimicrobial defense-related genes: IL6, IL8L2, CASP6, PTGS2, IRF7, AvBD9, AvBD10, and AvBD11. Moreover, fenugreek seeds altered the cecal microbial community by increasing the population of Firmicutes and decreasing the population of Actinobacteriota, Gemmatimonadota and Verrucomicrobiota at the phylum level and increasing

Indexed as

fenugreekgene expressionsimmune responsemicrobiota

Identifiers

PMID38393075
PMCPMC10891824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.