Evidence map›Paper›PMID 38393023›Full record

ArticleMarine drugs2024

Identification of Mortalin as the Main Interactor of Mycalin A, a Poly-Brominated C-15 Acetogenin Sponge Metabolite, by MS-Based Proteomics.

Elva Morretta, Alessandra Capuano, Gilda D'Urso, Antonia Voli, Matteo Mozzicafreddo, Sonia Di Gaetano, Domenica Capasso, Marina Sala, Maria Carmina Scala, Pietro Campiglia and 2 more

Abstract read
In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elva MorrettaDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0002-7244-0297
Alessandra CapuanoDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.
Gilda D'UrsoDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0002-4407-2781
Antonia VoliDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.
Matteo MozzicafreddoDepartment of Clinical and Molecular Sciences, Marche Polytechnic University, 60126 Ancona, Italy.ORCID 0000-0001-9835-8446
Sonia Di GaetanoInstitute of Biostructures and Bioimaging, Consiglio Nazionale delle Ricerche, Via Pietro Castellino 111, 80131 Napoli, Italy.ORCID 0000-0001-5523-3619
Domenica CapassoDepartment of Physics, Ettore Pancini, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy.ORCID 0000-0001-7201-3431
Marina SalaDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0003-2739-7215
Maria Carmina ScalaDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0001-5848-873X
Pietro CampigliaDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0002-1069-2181
Vincenzo PiccialliDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy.ORCID 0000-0003-4628-7548
Agostino CasapulloDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0002-2310-9426

Funding

Regione Campania CAMPANIA ONCOTERAPIE", CUP. B61G18000470007University of Salerno ORSA215145
6 · The paper itself

Abstract

Mycalin A (MA) is a polybrominated C-15 acetogenin isolated from the marine sponge

Indexed as

AcetogeninsHSP70 Heat-Shock ProteinsPoriferaAnimalsHeLa CellsHumansMolecular Docking SimulationProteomicsTumor Suppressor Protein p53AcetogeninsHSP70 Heat-Shock ProteinsmortalinTumor Suppressor Protein p53drug affinity responsive target stabilityheat shock proteinsmarine antitumoral compoundmolecular dockingmultiple reaction monitoringproteomicstargeted-limited proteolysis

Identifiers

PMID38393023
PMCPMC10890321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.