Evidence map›Paper›PMID 38392928›Full record

ArticlePharmacy (Basel, Switzerland)2024

Impact of the COVID-19 Pandemic on the Use of Antidepressants by Young Adults in the ASL TO4 Regione Piemonte (Italy).

Lucrezia Greta Armando, Raffaella Baroetto Parisi, Cristina Rolando, Mariangela Esiliato, Valeria Vinciguerra, Cecilia Bertiond, Abdoulaye Diarassouba, Clara Cena, Gianluca Miglio

Abstract read
In one paragraph

Article in Pharmacy (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lucrezia Greta ArmandoDepartment of Drug Science and Technology, University of Turin, Via Pietro Giuria 9, 10125 Turin, Italy.ORCID 0000-0001-9395-8047
Raffaella Baroetto ParisiStruttura Complessa Farmacia Territoriale ASL TO4, Regione Piemonte, Via Po 11, 10034 Chivasso, Italy.
Cristina RolandoStruttura Complessa Farmacia Territoriale ASL TO4, Regione Piemonte, Via Po 11, 10034 Chivasso, Italy.ORCID 0000-0001-6296-7928
Mariangela EsiliatoStruttura Complessa Farmacia Territoriale ASL TO4, Regione Piemonte, Via Po 11, 10034 Chivasso, Italy.
Valeria VinciguerraStruttura Complessa Farmacia Territoriale ASL TO4, Regione Piemonte, Via Po 11, 10034 Chivasso, Italy.
Cecilia BertiondStruttura Complessa Farmacia Territoriale ASL TO4, Regione Piemonte, Via Po 11, 10034 Chivasso, Italy.
Abdoulaye DiarassoubaStruttura Complessa Farmacia Territoriale ASL TO4, Regione Piemonte, Via Po 11, 10034 Chivasso, Italy.
Clara CenaDepartment of Drug Science and Technology, University of Turin, Via Pietro Giuria 9, 10125 Turin, Italy.ORCID 0000-0003-3718-7537
Gianluca MiglioDepartment of Drug Science and Technology, University of Turin, Via Pietro Giuria 9, 10125 Turin, Italy.ORCID 0000-0002-6602-2099

Funding

Università di Torino Ricerca Locale ex 60% - 2021 and 2022 to Gianluca Miglio e Clara Cena
6 · The paper itself

Abstract

The association between younger age and poorer mental health during the COVID-19 pandemic has been documented. Whether these changes were associated with a change in antidepressant (AD) use is not well understood. This study aimed to estimate the impact of the COVID-19 pandemic on AD use by young adults in the ASL TO4 Regione Piemonte (Italy). The impact of the pandemic on the weekly prevalence of AD users was assessed using interrupted time-series analysis with autoregressive integrated moving average models. A total of 1071 subjects (18-22 years with ≥1 AD dispensation) were included in the study. The observed prevalence was lower than the predicted value for several weeks after the introduction of the lockdown. However, it was consistently higher than the predicted values from week 134. The maximum difference between observed and predicted values (25 subjects per 10,000 young adults) was found at week 170. Changes in AD use were observed in both genders and were more pronounced for selective serotonin reuptake inhibitors. In conclusion, the impact of the COVID-19 pandemic on the mental health of young adults is likely to be significant in the coming years, which may place a future burden on pharmaceutical public health and community health.

Indexed as

antidepressant useARIMACOVID-19 lockdownmental health statusyoung adults

Identifiers

PMID38392928
PMCPMC10892218

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.