Evidence map›Paper›PMID 38392882›Full record

ArticlePathogens (Basel, Switzerland)2024

Bacterial Adaptive Memory in Methicillin-Resistant

Laia Fernández-Barat, Ruben López-Aladid, Nil Vázquez, Roberto Cabrera, Jordi Vila, Miquel Ferrer, Antoni Torres

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Laia Fernández-BaratCentro de Investigación Biomedica En Red-Enfermedades Respiratorias (CibeRes, CB06/06/0028) and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0001-7528-9636
Ruben López-AladidCentro de Investigación Biomedica En Red-Enfermedades Respiratorias (CibeRes, CB06/06/0028) and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Nil VázquezCentro de Investigación Biomedica En Red-Enfermedades Respiratorias (CibeRes, CB06/06/0028) and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Roberto CabreraCentro de Investigación Biomedica En Red-Enfermedades Respiratorias (CibeRes, CB06/06/0028) and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Jordi VilaUniversity of Barcelona, 08193 Barcelona, Spain.ORCID 0000-0002-8025-3926
Miquel FerrerCentro de Investigación Biomedica En Red-Enfermedades Respiratorias (CibeRes, CB06/06/0028) and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Antoni TorresCentro de Investigación Biomedica En Red-Enfermedades Respiratorias (CibeRes, CB06/06/0028) and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0002-8643-2167
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESBarcelona Institute for Global Health · ES

Funding

Centro de Investigación Biomédica en Red CIBER de enfermedades respiratorias -CIBERES (CB 06/06/0028, an initiative of ISCIII) and IDIBAPS group 2.693Government of Catalonia SGR 01148 (2021) from Generalitat de Catalunya to LFB,Institució Catalana de Recerca i Estudis Avançats ICREA academia to ATInstituto de Salud Carlos III ISCIII-FEDER (Code: PI18/00145) grant awarded to AT and LFB; Intramural Ciber pro-ject 2018 (ES18PI01X1-2021) awarded to AT and LFB; ISCIII-FOS (FI19/00090) grant awarded to RLASociedad Española de Neumología y Cirugía Torácica SEPAR grants 2016 (Code:208), 2019 (Code: 628) and 2023 (Code: 1428) awarded to LFB
6 · The paper itself

Abstract

objectivesTo evaluate the expression dynamics of biofilm genes in methicillin-resistant

methodsBiofilm was grown (24 h) in tryptic broth soy plus 0.25% glucose for a clinical MRSA isolate in planktonic state and after sessile growth named ETT-MRSA (S2, S3, S4, S5, S6, S7). Gene expression of five biofilm-related genes (

resultsThe MRSA isolates retrieved from ETT were capable of producing biofilms dependent on

conclusionsMRSA loses its biofilm gene expression in vitro, by adaptive features across multiple generations, as evidenced by the progressive downregulation of

Indexed as

BiofilmsGene Expression Regulation, BacterialIntubation, IntratrachealMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsBacterial ProteinsHumansBacterial Proteinsbiofilmendotracheal tubesgene expressionmethicillin-resistant Staphylococcus aureusnosocomial pneumoniaventilator-associated pneumonia

Identifiers

PMID38392882
PMCPMC10892081
OpenAlexW4391568153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.