Evidence map›Paper›PMID 38392876›Full record

ReviewPathogens (Basel, Switzerland)2024

Chronic Wasting Disease: State of the Science.

Jason C Bartz, Rebeca Benavente, Byron Caughey, Sonja Christensen, Allen Herbst, Edward A Hoover, Candace K Mathiason, Debbie McKenzie, Rodrigo Morales, Marc D Schwabenlander and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 25 citations in OpenAlex.

  1. Cellular PrPThe Journal of general virology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 3 countries.

Jason C BartzDepartment of Medical Microbiology and Immunology, Creighton University, Omaha, NE 68178, USA.
Rebeca BenaventeDepartment of Neurology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Byron CaugheyLaboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.
Sonja ChristensenDepartment of Fisheries and Wildlife, Michigan State University, East Lansing, MI 48824, USA.
Allen HerbstU.S. Geological Survey, National Wildlife Health Center, Madison, WI 53711, USA.
Edward A HooverPrion Research Center, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
Candace K MathiasonPrion Research Center, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0002-5920-4556
Debbie McKenzieDepartment of Biological Sciences, Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M9, Canada.
Rodrigo MoralesDepartment of Neurology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0000-0001-7766-5770
Marc D SchwabenlanderMinnesota Center for Prion Research and Outreach, Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Daniel P WalshU.S. Geological Survey, Montana Cooperative Wildlife Research Unit, University of Montana, Missoula, MT 59812, USA.ORCID 0000-0002-7772-2445
The Nc North American Interdisciplinary Chronic Wasting Disease Research Consortium Members
Colorado State University · USUnited States Geological Survey · USCreighton University · USMichigan State University · USNational Institutes of Health · USThe University of Texas Health Science Center at Houston · USUniversidad Bernardo O'Higgins · CLUniversity of Alberta · CAUniversity of Minnesota · US

Funding

Detection of PrionsZIAAI001086 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CAUGHEY, BYRON · 2009 to 2025
$18.1M
Structures and Activities of Prions and Prion Proteins ZIAAI000580 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CAUGHEY, BYRON · 2009 to 2025
$8.9M
Transmission and Pathogenesis of Chronic Wasting Disease (CWD)R01NS061902 · NINDS · COLORADO STATE UNIVERSITY · PI MATHIASON, CANDACE K. · 2009 to 2022
$5.3M
Shedding, retention and spreading of chronic wasting disease prions in the environmentR01AI132695 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Rodrigo Morales · 2017 to 2026
$4.6M
Detection and Characterization of Blood-borne PrionsR01AI112956 · NIAID · COLORADO STATE UNIVERSITY · PI MATHIASON, CANDACE K. · 2014 to 2024
$4.6M
Chronic Wasting Disease VaccinesR01AI156037 · NIAID · COLORADO STATE UNIVERSITY · PI MATHIASON, CANDACE K. · 2021 to 2025
$3.5M
Mechanisms of prion spread and establishment of infectionR01NS107246 · NINDS · CREIGHTON UNIVERSITY · PI BARTZ, JASON C, KINCAID, ANTHONY E. · 2018 to 2022
$2.4M
Infection-driven mechanisms associated with Alzheimer's disease pathologyRF1AG072491 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BARICHELLO, TATIANA, MORALES, RODRIGO · 2021 to 2021
$2.0M
Key molecular mechanisms of extraneural pathogenesis and transmission of TSEsR01NS056379 · NINDS · COLORADO STATE UNIVERSITY · PI ZABEL, MARK D · 2008 to 2012
$1.4M
Intramural NIH HHS ZIA AI001086NIAID NIH HHS R01 AI112956NIAID NIH HHS R01 AI132695NIAID NIH HHS R01 AI156037NIA NIH HHS RF1 AG072491NINDS NIH HHS R01 NS056379NINDS NIH HHS R01 NS061902NINDS NIH HHS R01 NS107246U.S. Department of Agriculture 23-7488-1682-CA
6 · The paper itself

Abstract

Chronic wasting disease (CWD) is a prion disease affecting cervid species, both free-ranging and captive populations. As the geographic range continues to expand and disease prevalence continues to increase, CWD will have an impact on cervid populations, local economies, and ecosystem health. Mitigation of this "wicked" disease will require input from many different stakeholders including hunters, landowners, research biologists, wildlife managers, and others, working together. The NC1209 (North American interdisciplinary chronic wasting disease research consortium) is composed of scientists from different disciplines involved with investigating and managing CWD. Leveraging this broad breadth of expertise, the Consortium has created a state-of-the-science review of five key aspects of CWD, including current diagnostic capabilities for detecting prions, requirements for validating these diagnostics, the role of environmental transmission in CWD dynamics, and potential zoonotic risks associated with CWD. The goal of this review is to increase stakeholders', managers', and decision-makers' understanding of this disease informed by current scientific knowledge.

Indexed as

DeerWasting Disease, ChronicAnimalsAnimals, WildHumansPrionsZoonosesPrionscervidsenvironmental prionsinterspecies transmissionPMCAprion diseaseRT-QuICzoonosis

Identifiers

PMID38392876
PMCPMC10892334
OpenAlexW4391470631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.