Evidence map›Paper›PMID 38392851›Full record

ReviewPathogens (Basel, Switzerland)2024

Mucosal Immunity against SARS-CoV-2 in the Respiratory Tract.

Hae-Eun Noh, Min-Seok Rha

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hae-Eun NohDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Min-Seok RhaDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0003-1426-7534
Yonsei University · KR

Funding

National Research Foundation of Korea, funded by the Ministry of Science & ICT RS-2023-00222762
6 · The paper itself

Abstract

The respiratory tract, the first-line defense, is constantly exposed to inhaled allergens, pollutants, and pathogens such as respiratory viruses. Emerging evidence has demonstrated that the coordination of innate and adaptive immune responses in the respiratory tract plays a crucial role in the protection against invading respiratory pathogens. Therefore, a better understanding of mucosal immunity in the airways is critical for the development of novel therapeutics and next-generation vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses. Since the coronavirus disease 2019 pandemic, our knowledge of mucosal immune responses in the airways has expanded. In this review, we describe the latest knowledge regarding the key components of the mucosal immune system in the respiratory tract. In addition, we summarize the host immune responses in the upper and lower airways following SARS-CoV-2 infection and vaccination, and discuss the impact of allergic airway inflammation on mucosal immune responses against SARS-CoV-2.

Indexed as

COVID-19COVID-19 VaccinesImmunity, MucosalRespiratory SystemSARS-CoV-2Adaptive ImmunityHumansImmunity, InnateCOVID-19 Vaccinesairwayallergic airwayCOVID-19mucosal immune responserespiratory tractSARS-CoV-2

Identifiers

PMID38392851
PMCPMC10892713
OpenAlexW4391253933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.