Evidence map›Paper›PMID 38392632›Full record

ArticleJournal of personalized medicine2024

Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study.

Antonios Dakanalis, Christina Tryfonos, Eleni Pavlidou, Konstantinos Vadikolias, Sousana K Papadopoulou, Olga Alexatou, Theofanis Vorvolakos, Maria Chrysafi, Dimitrios Fotiou, Maria Mentzelou and 5 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Antonios DakanalisDepartment of Mental Health, Fondazione IRCCS San Gerardo dei Tintori, Via G.B. Pergolesi 33, 20900 Monza, Italy.ORCID 0000-0002-2328-3862
Christina TryfonosDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, Greece.
Eleni PavlidouDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, Greece.ORCID 0000-0002-7764-3544
Konstantinos VadikoliasDepartment of Neurology, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Sousana K PapadopoulouDepartment of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, 57400 Thessaloniki, Greece.
Olga AlexatouDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, Greece.
Theofanis VorvolakosDepartment of Psychiatry, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Maria ChrysafiDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, Greece.
Dimitrios FotiouDepartment of Neurology, School of Medicine, Aristoteleio University of Thessaloniki, 54124 Thessaloniki, Greece.
Maria MentzelouDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, Greece.
Aspasia SerdariDepartment of Psychiatry, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Maria ChatzidimitriouDepartment of Biomedical Sciences, School of Health Sciences, International Hellenic University, 57400 Thessaloniki, Greece.ORCID 0000-0002-2101-4546
Sophia DimolianiDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, Greece.
Gerasimos TsourouflisSecond Department of Surgery, Propedeutic, National and Kapodistrian University of Athens, Laikon General Hospital, 11527 Athens, Greece.
Constantinos GiaginisDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, Greece.ORCID 0000-0003-2878-4831
University of the Aegean · GRDemocritus University of Thrace · GRInternational Hellenic University · GRAristotle University of Thessaloniki · GRAzienda Ospedaliera San Gerardo · ITNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Mediterranean diet (MD) is well-known as a diet which may exert a protective effect against neurodegenerative diseases, including multiple sclerosis (MS). To date, only a few clinical surveys have assessed the potential effects of the MD in patients with MS. The purpose of the present study is to evaluate the potential effects of MD compliance on disease disability, quality of life, physical activity, depressive symptomatology, and blood biochemical parameters related to nutritional status in MS patients, considering several socio-demographic, anthropometric, and lifestyle characteristics.

methodsThis is a cross-sectional study conducted on 558 adults with MS aged 18-64 years. Relevant questionnaires were utilized to evaluate socio-demographic and anthropometric parameters, disease disability (Expanded Disability Status Scale, EDSS), multidimensional health-related quality (MS Quality of Life-54, MSQOL-54), physical activity levels (International Physical Activity Questionnaire, IPAQ), depression (Beck Depression Inventory II, BDI-II), and MD adherence (MedDietScore), while several blood biochemical parameters were retrieved from the patients' medical records.

resultsEnhanced MD compliance was independently associated with a decreased frequency of overweight/obesity, as well as abdominal obesity, in patients suffering from MS. Elevated MD compliance was also independently associated with a decreased incidence of advanced disease disability, a higher prevalence of elevated physical activity, an improved quality of life, and lower depressive symptoms, as well as higher levels of certain blood biochemical parameters, which are effective indicators of iron deficiency and malnutrition.

conclusionsThe present study found that higher MD adherence may slow down disease disability, promoting a better quality of life and mental health in adults with MS. Future prospective surveys are required to obtain conclusive results.

Indexed as

disease disabilitymalnutritionMediterranean dietmultiple sclerosisneurodegenerative diseasesobesityphysical activityquality of lifeserum biomarkerssymptoms’ severity

Identifiers

PMID38392632
PMCPMC10890719
OpenAlexW4391748074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.